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… with a view to developing a deeper understanding of sequence-based gene function. … B.Sc. (HONS) – University of … tool for targeted and genome-scale gRNA design and sequence extraction for prokaryotes and eukaryotes. …

… illness, disease risk, and treatment response due to fungal genomics internship with Igor Grigoriev. Portia Mira …

… the process hinges on referencing to existing genome sequences.  Some of these proteins are what the scientists … artificial intelligence to decode the language of protein sequences and obtain hints of their possible functions. Yet … efforts were limited to the realm of already-known protein sequences.  “In this endeavor, we have not only ventured …

Schmutz is the Plant Program Lead at the JGI. Sarah:  Why is a resource like this important to the field of plant …

… genomes of uncultivated giant viruses from environmental sequences across the globe, then using these sequences to make inferences about the biogeographic … giant virus genomes reconstructed from environmental sequences is still challenging and even with this study we …

… at virus infections. Their genomes include short DNA sequences that code for CRISPR systems, which help bacteria … resist foreign genetic elements by incorporating short sequences from infecting viruses and phages. In these sequences are virus fragments called spacers, that indicate …

… under laboratory conditions, their genomes can’t be sequenced using traditional approaches. Identifying and … of metagenome-assembled genomes (MAGs) directly from sequenced environmental samples without needing to cultivate … – that’s pretty remarkable.” Adding Value Beyond Genome Sequences Much of the data had been generated from …

… expressing a given BGC in various hosts, availability of sequenced genomes, and computing resources needed to predict BGCs from available genome sequences. The DOE Joint Genome Institute (JGI), a DOE …

… messenger RNA", and that somewhere in the mess of genetic sequences lurks the next cool virus – if only our code would …