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Boosting Small Molecule Production in Super “Soup”
Do metabolic pathways from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: … The work started with yeast strains engineered by Alper’s team to convert the sugar glucose to the products including …
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FICUS-NERSC/KBASE
The mission of the Joint Genome Institute is to serve the scientific … The ranked proposal list, along with a recommendation from management at JGI and the other participating … Management Office.  At the completion of a project, the JGI makes the assemblies, gene annotations, and analyses …
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10 From JGI on the 2019 Highly Cited Researchers List
Clarivate Analytics, formerly the IP & Science arm of Thomson Reuters, has released their 2019 list of Highly Cited … Woyke , Biology & Biochemistry category Some highlights from projects each of these researchers were involved in … in the Proceedings of the National Academy of Sciences, the team established community gardens of switchgrass plants in …
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How Filamentous Fungi Sense Food
… in the model fungus  Neurospora crassa . The Science A team led by researchers at the University of California, … breaks down plant cell wall materials including lignin, cellulose and hemicellulose. The Impact N. crassa is the … break down the components of plant cell walls, which range from simple to complex carbohydrates, and then convert them …
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A Natural Mechanism Can Turbocharge Viral Evolution
Understanding how a fundamental mechanism of evolution allows microbes to adapt to changing environments. The … target on the microbial cell’s membrane. Two decades ago, a team discovered a group of viruses that had in their genomes … and viral genomes, as well as genomes sampled all at once from the same environment, called metagenomes. Why? Simon …
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Data Policy
… are subject to the following Data Policy. It is our mission to support open data and information sharing. We also … Proposals accepted before FY22 are transitioning away from producing use-restricted data. JGI proposals typically … project level to expedite the change in data policy. Data from projects for which JGI has not yet received samples as …
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River microbiomes from around the world: Kelly Wrighton
Kelly Wrighton and her group at Colorado State University in Fort … sequencing the world’s river microbiomes. And they’re using team science to do it.   …
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Doubling Down on Known Protein Families
Using a novel computational approach, researchers confirm microbial diversity is … at protein function within them. The work was led by a team of scientists at the U.S. Department of Energy (DOE) … ‘Dark Matter’ Microbial communities living everywhere from soils and stomachs to the deep sea are capable of doing …
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Dispatches From JGI Interns
… with JGI mentors. In this episode, hear two interns from the 2021 cohort describe their deep dives into genomics, computational tools, and big data.  …
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Marchantia Pangenome Highlights Adaptive Nature of Plant Lineages
… involved in adaptations seen in later plant lineages. The team found that some of the adaptation strategies used by … studies. Its place among early-diverging plant lineages makes it ideal for comparative genomics studies, offering … no. DE-AC02-05CH11231. This project received funding from the European Research Council under the European …
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Metabolomics Program
… metabolites, genes, and proteins. It also enables exploration of energy and nutrient exchange, as well as microbial and … mass spectrometry-based methods to analyze metabolites from a wide range of biological and environmental samples — … with genomics, transcriptomics, imaging, and other data from EcoFAB systems can provide novel insights into the …
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Bacteria and Fungi Divvy Up the Work in Forest Floor
Bacterial enzymes play second fiddle to those from fungi when it comes to breaking down tough plant … in the complex organic matrix of the forest floor, a team of researchers have found that there is a striking … suggest that fungi are breaking down plant fibers, like cellulose and lignin. Bacteria, on the other hand, appear to …
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