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Single Cell Research Group
Bacteria and Archaea has steadily been widening since 2005. This gap is also reflected in the strongly biased … genomes are critical to serve as phylogenetic anchors for metagenomes studies.  While uncovering the metabolic potential … virus diversity and host interactions through global metagenomics.” Nature 578(7795): 432-436 (2020). Seshadri R., …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… a more systematic picture through single-cell and metagenomic sequencing. A team co-led by Mária Džunková, … and archaeal cells — and detected the virus in 34 hosts or 26 percent of the single cells. Metagenomics sequencing then allowed the team to ask, for the …
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Exploring Phages at JGI
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Natural Prodcast Episode 3: The Primer, Part 3
… and listen to the first two parts ( part 1 is here and part 2 is here ) so you understand what’s happened so far in the … me to check her stat and she was absolutely correct. Since 2010 there have been eight new antibiotics added to the … from your cultures, but then you’re going to find another 20 or 30 secondary metabolism pathways that you didn’t even …
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How to Target a Microbial Needle within a Community Haystack
… for capturing the genetic make-up of specific uncultivated microbes from complex environmental samples. The Science A … of the microbial world through bulk community sequencing (metagenomics) and single-cell genomics, the vast majority of … User Facility, is supported under Contract No. DE-AC02-05CH11231. This study was funded by the Max Planck Society. …
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Rex Malmstrom
Microscale Applications group. Before joining the JGI in 2010, he made the first ever measurements of in situ growth … genetic material, thus bypassing the need to culture these microbes in the lab. After joining the JGI, he formed the … His group also handles the Stable Isotope Probing (SIP) Metagenomics pipeline  that reveals in situ functional …
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JGI@25: Following Fungi that Pry Apart Plant Polymers
… 2022 marks the JGI’s 25th anniversary. Over the last year, … evolved these really tough cell wall materials that keep microbes — and the enzymes that would be produced by … genomics and transcriptomics to discover another advantage these fungi wield: the capacity to form enzyme …
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Robert Bowers
Bob uses single-cell genomics and metagenomics to explore how microbes influence people and the environment. This includes … studying the diversity, physiology and community ecology of microbes sampled from the natural environment. …
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Hiroshi Otani
Since joining the DOE Joint Genome Institute in 2016, Dr. Otani has been studying secondary metabolism in microbes, particularly actinomycetes. His research activity … particularly interested in understanding how, when and why microbes decide to produce which metabolites. … BS, …
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A Shrubbier Version of Rubber
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A Natural Mechanism Can Turbocharge Viral Evolution
… how a fundamental mechanism of evolution allows microbes to adapt to changing environments. The Science The … the discovery of more than 30,000 DGRs in this analysis, a 20-fold increase over what was previously known, throws open … sampled all at once from the same environment, called metagenomes. Why? Simon Roux, who led the research team and is …
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Supercharging SIP in the Fungal Hyphosphere
… communities, with results published in the  November 2022 issue of Microbiome . High-throughput stable isotope … it. The isotopes are incorporated into the DNA of specific microbes who consume the labeled food or water. Later, their … which microorganisms used the labeled substance and which microbes did not. This is normally an arduous wet lab …
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