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How to Target a Microbial Needle within a Community Haystack
… of the microbial world through bulk community sequencing (metagenomics) and single-cell genomics, the vast majority of … allow researchers to focus on specific microbes within metagenome samples and associate their sequences with their … User Facility, is supported under Contract No. DE-AC02-05CH11231. This study was funded by the Max Planck Society. …
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Natural Prodcast Episode 7: Ben Shen
… on DNA sequencing and synthetic biology. But also the metagenomics and gut microbiome, as I think that it’s like a … right? BEN: Yeah, yeah. Well, we are at [10 to the] minus 12 [Molar concentration]- is sufficient to kill cells. So … enediynes to the market in 2001 with a drug called Mylotag. Wyeth was later acquired by Pfizer in 2009. So, a …
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JGI Earth Month: Healthy Streams, Nutritious Microbes?
In April 2020, we mark both the 50th celebration of Earth Day on April 22, and DNA Day on April 25. As both Earth and DNA are close …
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JGI Announces 2023 Community Science Program Awardees
… to the proposers of the 19 proposals selected for the 2023 Community Science Program call of the U.S. Department of … on our website. The approved proposals start October 1, 2022. See the full list of awardees below: …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… scientists usually employ two different methods; shotgun metagenomic sequencing and single-cell sequencing. For years, … genomes from microorganisms are shotgun (group) metagenomic sequencing and single-cell (individual) … like plasmids, the picture is far from complete.  In 2021 , scientists at St. Jude Children’s Research Hospital …
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Crops as Tough as World Cup Turf
… to be the same species that covered World Cup pitches in 2022.                     …
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Uri Neri
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JGI Announces 2025 New Investigator Portfolio
… a list of researchers whose proposals were accepted for 2025. Utilizing the JGI’s resources, these researchers will … call; the next deadline for proposal submission is Sept. 9, 2025, for inclusion in the November 2025 review. You can …
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Better Crops With a Pointillist Approach to Plant Genomics
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
… to  Euryarchaeota .  Finding Methane-Making Microbes with Metagenomics  By leveraging metagenomics to sample the entirety of a microbial community … from different phyla are capable of methanogenesis. Using metagenomics eliminates confirmation bias, because it enables …
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Uncovering Novel Genomes from Earth’s Microbiomes
… in a wide range of research fields. A public repository of 52,515 microbial draft genomes generated from environmental … and the  DOE Systems Biology Knowledgebase (KBase) . Metagenomics is the study of the microbial communities in the … sequencing and analysis. “Using a technique called metagenome binning, we were able to reconstruct thousands of …
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Cataloging the Microbes that Manage the Health of River Systems
National Laboratory. The JGI sequenced over 1,000 metagenomes and established standardized sequencing protocols … Biological and Environmental Research (BER) grants DE-SC0023084, DE-SC0021350, and DE-AC02-05CH11231. Partial support … were also funded under the RC-SFA at PNNL by DOE BER ESS. Metagenomic and metatranscriptomic sequencing was performed at …
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