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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the … method called Primary Template-Directed Amplification (PTA) yields a much higher completion, above 80% in most cases. … difficult to link the connections to them from the genetic elements that scientists have found, e.g. plasmids and other …
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Mike Sneddon
… Department at the Joint Genome Institute. His team of engineers and scientists builds and operates the data and … science.  Dr. Sneddon is an accomplished leader in data, software, compute, and AI for large-scale genomics and lab … Prior to joining JGI in late 2025, he served as Director of Scientific Computing at Predicine, an NGS-based clinical …
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Community Science Program
… synthesis, and metabolomics at the JGI for projects of relevance to Department of Energy (DOE)  Mission Areas . Through this program, the … genome science-based scientific research from a broad range of disciplines. Three calls fall under the umbrella of our … more customized analysis, the JGI also participates in publication of results. See more details on our Review …
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FICUS-NERSC/KBASE
… The mission of the Joint Genome Institute is to serve the scientific … relevant bioenergy and environmental problems.  The mission of the National Energy Research Scientific Computing Center … ( NERSC ) is to accelerate scientific discovery at the DOE Office of Science through high performance computing (HPC) …
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Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growth
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Axel Visel
… Programs, he focuses on the development and implementation of strategic initiatives at the JGI. Dr. Visel received his … methods for elucidating the gene regulatory landscape of vertebrate genomes, which led to the discovery of thousands of genetic switches implicated in developmental …
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Disclaimer
… resides on a computer system funded by the U.S. Department of Energy. Anyone using this system consents to monitoring of this use by system or security personnel. … neither the United States Government nor the University of California nor any of their employees, makes any …
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RECAP: Keynote Speakers Talk Innovation at 2022 JGI Annual Meeting
… The JGI was honored to host some of the brightest minds in genetics as part of our  2022 Annual Meeting . The meeting was a hybrid … of UC Riverside, who discussed her work on transposable elements and how understanding these genes has helped pave … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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An Integrated Dataset to Understand Ecosystem Interaction
… Research yields a comprehensive tree and soil dataset for … and integrated data set will help identify how different elements of the ecosystem interact and respond to changes in the … This research was sponsored by the U.S. Department of Energy, Office of Science, Biological and Environmental …
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Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet
… Survey of Setaria's natural diversity reveals seed dispersal in … Center (Danforth Center) drove up and down the highways of the continental United States, occasionally pulling over … for domesticated crops because it leads to reduced harvest yields. Over thousands of years, farmers have selected for …
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Who We Are
…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national … at Lawrence Berkeley National Laboratory. The JGI consists of 225 researchers and support staff in the Integrative … The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a …
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Mining Metagenomes for Cas Proteins
… Institute.  The Science Researchers report the discovery of miniature Clustered Regularly Interspaced Short … Integrated Microbial Genomes and Microbiomes (IMG/M) suite of tools managed by the U.S. Department of Energy (DOE) … in bacteria that confers resistance to foreign genetic elements by incorporating short sequences from infecting …
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