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A Cost-Efficient Way to Convert Yeast into a Cell Factory for Hydroxyapatite
… Innovative technology from this biomanufacturing collaboration is available for … hydroxyapatite, a high-value biomaterial with a wide range of industrial applications. The team was led by researchers at two U.S. Department of Energy national user facilities – the DOE Joint Genome …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … Over the years more than 3,400 genomes have been sequenced from curated DSMZ isolates, for which quality DNA has been … resource, but also yielding and supporting many high-impact publications ,” emphasized Markus Göker, who managed the …
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Game On: High School Students Drive Everglades Metagenomics Study
… In late June, Kathleen Lail, a member of JGI’s Sample Management Group, attended a conference in … that the project had already received enthusiastic support from the JGI Director, Nigel Mouncey. Jonathan credits his … and organic carbon concentration. From Field Studies to Publication Together as a class, the students learned about …
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Metabolomics
… functional genome annotation, improves understanding of the role small molecules play in diverse biological … sheds light on nutrient cycling, and leads to the discovery of new molecules and pathways. The JGI Metabolomics Platform delivers rich metabolite profiles from diverse biological and environmental samples using …
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Natural Prodcast Episode 1: The Primer, Part 1
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hey there, and welcome to the … Laboratory. Being a User Facility means that scientists from all over the world bring us big problems related to …
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JGI@25: From Life at the Extremes to Editing Genomes
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … collection of publicly accessible metagenomic datasets from a wide variety of ecosystems around the world, … nature was using it to do something important.” Related Publications:  A scoutRNA Is Required for Some Type V …
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Mining Metagenomes for Cas Proteins
… Cas14 proteins discovered from JGI’s IMG/M database and biochemically characterized at … Institute.  The Science Researchers report the discovery of miniature Clustered Regularly Interspaced Short … to develop a Cas14-DETECTR that allows for CRISPR-based detection of ssDNA pathogens. With few exceptions, the Cas14 …
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Identification of novel biomass‐degrading enzymes from genomic dark matter: Populating genomic sequence space with functional annotation
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Bacterial Genome Annotation
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Getting to the Bottom of Fungal Functions Across Earth’s Forests
… Across four forests, researchers have leveraged data from the 1000 Fungal Genomes project to form new connections … registers the sound — one thing is for sure: there are lots of fungi around. Within a forest’s soil, hundreds of species … over 2,000 fungal genomes. The JGI sequenced, assembled and annotated these genomes in collaboration with dozens of …
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Len Pennacchio
… Joint Genome Institute and has focused on applying state-of-the-art molecular methods to address wide-ranging … Scientist at Lawrence Berkeley Laboratory, and Adjunct Professor at UC Berkeley. Dr. Pennacchio received his Ph.D in 1998 from the Department of Genetics at Stanford University where …
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Intraspecific comparison and annotation of two complete mitochondrial genome sequences from the plant pathogenic fungus Mycosphaerella graminicola
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