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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and … engineered root bacteria  Pseudomonas  and Ralstonia with enzymes that make phosphate bioavailable for plants. When … bacterial strains as part of the Community Science Program (CSP)  Functional Genomics proposal call. …
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How Maize Makes An Antibiotic Cocktail
… protects it against infections — using surprisingly few enzymes. The Science Maize ( Zea mays ) produces a plethora … Science Program . And the work is part of a  larger CSP Functional Genomics proposal to understand terpene  … a DOE Joint Genome Institute Community Science Program (JGI-CSP) grant (CSP2568 to P.Z., ES and AH), and by a …
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Nigel Mouncey
… traits. Dr. Mouncey has successfully built integrated and highly effective multi-disciplinary teams, and today, … DOE National Laboratories, the Community Science Program (CSP), and external collaborations. The Director ensures the … Reference Genomes. Cell Genomics 2: 100213Nayfach S et al. 2021. A genomic catalog of Earth’s microbiomes. Nat …
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Natural Prodcast Episode 1: The Primer, Part 1
ALISON: Hmm. It kind of – it’s kind of like I’m smelling bacterial perfume. I mean – but it’s purposeful so it’s some … it’s not known as far as I could tell.  ALISON: It could be bacterial blankets, or coats, or water bottles, in a … communicate – with chemicals.  ALISON: We could be smelling bacterial phone calls. When it rains. DAN: All right. Okay, …
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IMG-ABC: new features for bacterial secondary metabolism analysis and targeted biosynthetic gene cluster discovery in thousands of microbial genomes
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Tanja Woyke
… and assumed the Deputy Director of User Program position in 2021. In addition to her JGI appointment, she also holds an … Eberhard Karls University of Tübingen, Germany … 2018-2023 Highly Cited Researcher, Biology and Biochemistry, top 1%, … matter. Nature 499, 431-437. Hess et al. 2011. Metagenomic discovery of biomass-degrading genes from cow rumen. Science …
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Enlarging Windows into Understanding Gene Functions
Technologies Group. In an article published November 25, 2021 in Nature Methods , JGI researchers led by co-first … approaches of Biotin DAP-seq and multiDAP allows for ultra high throughput discovery of transcription factor binding … proposal through the JGI’s Community Science Program (CSP) focuses on a fungal comparative ENCODE project known as …
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JGI@25: Following Fungi that Pry Apart Plant Polymers
… tough cell wall materials that keep microbes — and the enzymes that would be produced by microorganisms — out,” … 2012, O’Malley has worked with the JGI to understand the enzymes these organisms use to bust biomass apart. She and … complexes that work like assembly lines for efficiency.  In 2021, her team saw that four strains of anaerobic fungi …
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A perspective: Metatranscriptomics as a tool for the discovery of novel biocatalysts
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Discovery of Novel Plant Interaction Determinants from the Genomes of 163 Root Nodule Bacteria
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Modulation of sensory perception by hydrogen peroxide enables Caenorhabditis elegans to find a niche that provides both food and protection from hydrogen peroxide
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Crysten Blaby-Haas
JGI and Molecular Foundry for genome-encoded biomaterial discovery, design, and engineering. … PhD, Microbiology and … Niyogi KK, Schmutz J, Theg SM, Blaby-Haas CE, Merchant SS. (2021) Widespread polycistronic gene expression in green … PNAS  118 (7) e2017714118 Foflonker F and Blaby-Haas CE. (2021) Co-locality to co-functionality: Eukaryotic gene …
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