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Simon Roux Named 2025 ASM Microbiome Data Prize Awardee
… Congratulations to US Department of Energy (DOE) Joint Genome Institute (JGI) staff scientist … Society for Microbiology (ASM). Roux leads the Viral Genomics group within the JGI Metagenome Program, and … The Prize also recognizes innovative and impactful analysis of microbiome data that has changed our …
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Polar Phytoplankton Need Zinc to Cope with the Cold
… Antarctic algae need their vitamins; zinc fuels some of their most important functions. Even in the chilly waters … expanded genes for proteins requiring zinc. Co-expression analysis as well as laboratory culture experiments showed … collaboration with the JGI Algal Program, which explores genomics of algal diversity and biology to support basic …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… The Science Within the archaeal domain, there is a group of tiny hitchhikers. These organisms are abundant and yet … interactions are difficult to study in the lab. Metagenomics provides new views of these relationships.  Recently , researchers used population genomics to find that while archaeal hitchhikers may often …
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Hiroshi Otani
… technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … BS, Engineering, Tokyo Institute of Technology Master's, Biotechnology, University of Tokyo PhD, Biotechnology, University of Tokyo … 2023 Feb 17;50(1):kuad005. Otani H, Udwary DW, Mouncey NJ. Comparative and pangenomic analysis of the genus …
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Neha Varghese
… key role is to design, benchmark, and apply bioinformatics software to enable analysis and interpretation of genomic and metagenomic data … science and projects through implementation of advanced analysis pipelines and tools as well as development and …
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Better Genome Editing for Bioenergy
… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … tool will make the right cut, researchers created a set of guide RNAs that were effective against 94 percent of the genes in a lipid-prolific yeast. The Impact The team … MB) and NSF  1706545 (IW). HA and JW were supported by the Office of Naval Research under grant  N00014-15-1-2785 . JW …
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Leo Baumgart
… his doctoral research in synthetic biology and microfluidics at the University of California, San Diego. As the Sequencing Technology … plant tissues. Dr. Baumgart focuses on expanding functional genomics capabilities through process automation and method … BS in Biochemistry and Cell Biology, University of California, San Diego PhD in Molecular Biology, …
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Rex Malmstrom
… Dr. Malmstrom is a Staff Scientist and leader of the Microscale Applications group. Before joining the JGI … Applications group to operate a similar single-cell genomics pipeline that provides JGI users access to the … His group also handles the Stable Isotope Probing (SIP) Metagenomics pipeline  that reveals in situ functional …
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Katherine Louie
… efforts to expand the metabolomics capabilities and product offerings for JGI users.  Using cutting-edge mass … spectrometry workflows for polar and nonpolar metabolite analysis, creation of large metabolite databases by running … standards, and development of high-throughput untargeted analysis pipelines.  Beyond profiling over 10k samples/year, …
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Calculating the Costs of Multiple Switchgrass Gene Copies
… A collaborative team led by researchers at the University of Texas (UT) at Austin, the HudsonAlpha Institute for Biotechnology (HudsonAlpha), and the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, has discovered that the …
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Ancient Algae Reveal Secrets of Plant Evolution
… 600 million years ago. The Science By studying the genes of land plants’ closest algal relative,  Zygnematophyceae , scientists have enhanced our understanding of how early plants transitioned from water to land. Key … life.  These led to highly detailed assemblies for three strains of  Zygnema circumcarinatum . Published  May 2024 …
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JGI Launches Latest Strategic Plan
… For the Joint Genome Institute, the end of 2018 was marked by a celebration of contributing over one “petabase” – a quadrillion … has begun to the June dedication event of the Integrative Genomics Building—the new home of the JGI and KBase in the …
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