Search

… with a view to developing a deeper understanding of sequence-based gene function. … tool for targeted and genome-scale gRNA design and sequence extraction for prokaryotes and eukaryotes. … al., Bacterial genome editing by coupling Cre-lox and CRISPR-Cas9 systems. PloS one. 15: 11. 2020 Blaby & Cheng, …

… distinguish which gene belongs to each individual microbial species within a community. Therefore, the process hinges on referencing to existing genome sequences.  Some of these proteins are what the scientists … artificial intelligence to decode the language of protein sequences and obtain hints of their possible functions. Yet …

… comparative genomic analyses.   The Impact There are 900 species of eucalyptus. The trees are fast-growing plantation … using advanced technologies to reconstruct the complete sequences of individual chromosomes. The team describes the … hypothesizes the difference might not be due to repeated sequences, but rather the more accurate assembly of regions …

… environments. The Science Cyclic di-GMP (Guanine Monophosphate) is found in nearly all types of bacteria and … Ec YcgR, within the Nano-lantern scaffold. They then mined sequence databases for homologous YcgR proteins and chose a … These 92 homologues were synthesized as codon optimized sequences and cloned into the Nano-lantern scaffold. Because …

… Over 40 percent of the cereal crop’s genes respond to drought stress. The Science Fields of drooping … conventional food crops. For that reason, its genome was sequenced by the JGI in 2009 and it is considered to be … diseases are well known to be partially due to the DNA sequence that makes up an individual’s genome. The genes of …

… with the HudsonAlpha Institute for Biotechnology, which specializes in genome improvement for plants. As part of … Plant Gene Atlas in  Nucleic Acids Research . The project spans 15 years and involves more than 17 research groups. … Schmutz is the Plant Program Lead at the JGI. Sarah:  Why is a resource like this important to the field of plant …

… genomes of uncultivated giant viruses from environmental sequences across the globe, then using these sequences to make inferences about the biogeographic … communities from freshwater ecosystems, including, respectively, the northern Lakes of Canada, the Laurentian …

… metagenomics with other omics approaches, including especially metatranscriptomics, to better highlight and … single-cell resolution assays that can be targeted towards specific phages and/or hosts. To that end, the JGI Viral … Roux, S. and Emerson, J. (2022) Diversity in the soil virosphere: to infinity and beyond? Trends in Microbiology. 30, …

… community able to not just analyze but also create DNA sequences mimicking an array of microbial life. By … is capable of discovering and modelling complex biological sequences such as biosynthetic gene cluster structures. … work with biotechnology companies including the bioeconomy space, trying to explore whether we can leverage this model …

… microscopic water mold, genetically related to such aquatic species as diatoms and kelp. Dubbed Phytopthora ramorum … Death or by its acronym, SOD. Of the dozens of Phytophthora species, the most globally-recognizable relative of SOD is … of millions of trees in California alone. With the genome sequence in hand, the UC team led the charge to develop …

… novel secondary metabolites for multiple applications. Despite advances in sequencing technologies and computational … under laboratory conditions, their genomes can’t be sequenced using traditional approaches. Identifying and … of metagenome-assembled genomes (MAGs) directly from sequenced environmental samples without needing to cultivate …

… human-induced climate change , a new study suggests, is displacing these important cold-water communities of algae … than previously suspected. “That would cause significant consequences on the entire food web, and therefore ecosystem … After isolating the algal communities on filters, they sequenced DNA ‘marker’ gene sequences to identify the …