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Genome sequences of key bacterial symbionts of entomopathogenic nematodes: Xenorhabdus cabanillasii DSM17905, Xenorhabdus ehlersii DSM16337, Xenorhabdus japonica DSM16522, Xenorhabdus koppenhoeferii DSM18168, and Xenorhabdus mauleonii DSM17908
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David Goodstein
… equipment manufacturer KLA-Tencor before joining the JGI in 2002. Initially focused on building tools to facilitate expert … et al., 2023. JGI Plant Gene Atlas: an updateable transcriptome resource to improve functional gene …
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Dealing with Drought: Uncovering Sorghum’s Secrets
… conventional food crops. For that reason, its genome was sequenced by the JGI in 2009 and it is considered to be a Flagship Plant. By … diseases are well known to be partially due to the DNA sequence that makes up an individual’s genome. The genes of …
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Doubling Down on Known Protein Families
… big the room is.  A new study  published online Oct. 11, 2023 in  Nature highlights the vast array of functional … the process hinges on referencing to existing genome sequences.  Some of these proteins are what the scientists … artificial intelligence to decode the language of protein sequences and obtain hints of their possible functions. Yet …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… genomes of uncultivated giant viruses from environmental sequences across the globe, then using these sequences to make inferences about the biogeographic … out and characterize uncultivated viruses. For instance, a 2018 study from a JGI-led team uncovered giant viruses in …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of … of millions of trees in California alone. With the genome sequence in hand, the UC team led the charge to develop … … Publication: Tyler BM et al. Phytophthora genome sequences uncover evolutionary origins and mechanisms of …
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Plotting a Model for Virus-Host Warfare Deep Below Ground
… at virus infections. Their genomes include short DNA sequences that code for CRISPR systems, which help bacteria … resist foreign genetic elements by incorporating short sequences from infecting viruses and phages. In these … do so, they compared samples collected from an aquifer in 2012 and 2018 against a biofilm sample collected in 2018. …
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Uncovering Novel Genomes from Earth’s Microbiomes
… under laboratory conditions, their genomes can’t be sequenced using traditional approaches. Identifying and … in a wide range of research fields. A public repository of 52,515 microbial draft genomes generated from environmental … of metagenome-assembled genomes (MAGs) directly from sequenced environmental samples without needing to cultivate …
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Computationally Classifying Fungal Lifestyles
Machine learning methods were applied on sequenced fungal genomes to classify gene families. The … through the 1000 Fungal Genomes Project, including 55 newly-sequenced species.  The Impact The class  Dothideomycetes … (green). (From Haridas S et al.  Studies in Mycology , 2020.) Using whole genome data from newly sequenced genomes, …
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Nigel Mouncey
Dr. Mouncey joined the DOE Joint Genome Institute in 2017 as the fourth Director in its 27-year history. He has a wealth of managerial experience from almost 20 years in the Industrial Biotechnology private sector, as …
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Yasuo Yoshikuni
… has been head of the DNA Synthesis Science Program since 2015. The mission of this program is to harness the power of … discovery and applications. This program has supported over 250 projects since it started. At the JGI, Dr. Yoshikuni … efficient than glycolysis., Nature Chemical Biology , 2024 Dubinkina et al., A transcriptomic atlas of acute …
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A Complex Confection Decoded: Sugarcane Reference Genome
… partly enabled by the JGI’s Community Science Program; in 2018, a monoploid reference sequence of sugarcane was published as a step forward in … .   … The work (proposal: https://doi.org/10.46936/10.25585/60001084 and …
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