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Viral Genomics Group
… Microbes drive critical ecosystem functions and affect global nutrient cycling, however they do so under … While an ever-increasing number of phage and virus genomes have been assembled and reported … metagenomics with other omics approaches, including especially metatranscriptomics, to better highlight and …
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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… chemiluminescent biosensors shed light on how bacteria function and colonize diverse environments. The Science Cyclic di-GMP (Guanine Monophosphate) is found in nearly all types of bacteria and … Ec YcgR, within the Nano-lantern scaffold. They then mined sequence databases for homologous YcgR proteins and chose a …
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Dealing with Drought: Uncovering Sorghum’s Secrets
… Over 40 percent of the cereal crop’s genes respond to drought stress. The Science Fields of drooping … conventional food crops. For that reason, its genome was sequenced by the JGI in 2009 and it is considered to be … This research was funded in part by DOE Grant DE-SC0014081 (to N.V., B.C., …
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New and Improved: Eucalyptus Reference is Now Accessible
… improved genome assembly to support targeted tree breeding for the bioeconomy.   The Science Researchers report a new … comparative genomic analyses.   The Impact There are 900 species of eucalyptus. The trees are fast-growing plantation … using advanced technologies to reconstruct the complete sequences of individual chromosomes. The team describes the …
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Doubling Down on Known Protein Families
… Using a novel computational approach, researchers confirm microbial diversity is wilder than ever. Imagine … distinguish which gene belongs to each individual microbial species within a community. Therefore, the process hinges on referencing to existing genome sequences.  Some of these proteins are what the scientists …
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A Collaboration to Improve Plant Genome Annotations Across Species
… works in partnership with the HudsonAlpha Institute for Biotechnology, which specializes in genome improvement for plants. As part of … Schmutz is the Plant Program Lead at the JGI. Sarah:  Why is a resource like this important to the field of plant …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… JGI-led team significantly expands the global diversity of large and giant … genomes of uncultivated giant viruses from environmental sequences across the globe, then using these sequences to … communities from freshwater ecosystems, including, respectively, the northern Lakes of Canada, the Laurentian …
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Ian Blaby
… Since 2019 Dr. Blaby heads the DNA synthesis platform at the Joint Genome Institute, where he leads three groups focused on HTP DNA design and assembly, strain engineering … with a view to developing a deeper understanding of sequence-based gene function. … B.Sc. (HONS) – University of Wales, Cardiff, Genetics Ph.D. – University of Cambridge., …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… on environmental data, a new JGI tool more accurately facilitates microbial genome discoveries. Unlocking the … community able to not just analyze but also create DNA sequences mimicking an array of microbial life. By … work with biotechnology companies including the bioeconomy space, trying to explore whether we can leverage this model …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … microscopic water mold, genetically related to such aquatic species as diatoms and kelp. Dubbed Phytopthora ramorum … of millions of trees in California alone. With the genome sequence in hand, the UC team led the charge to develop …
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Uncovering Novel Genomes from Earth’s Microbiomes
… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary metabolites for multiple applications. Despite advances in sequencing technologies and computational … under laboratory conditions, their genomes can’t be sequenced using traditional approaches. Identifying and …
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FICUS Overview
… The Facilities Integrating Collaborations for User Science (FICUS) initiative was established in 2014 to encourage and … All proposals undergo technical review by JGI staff as well as staff at the other participating facilities, … Following DOE approval, project managers negotiate project specifics with PIs (including JGI scientists as needed), and …
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