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… A team has optimized a crucial part of CRISPR-Cas9 … Cas9 needs guide RNA to lead it to the correct sequence to snip — but not all guides are effective. To … approach: CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, …

… A workflow for capturing the genetic make-up of specific … The Impact Despite great strides in generating genome sequences for members of the microbial world through bulk … microbes within metagenome samples and associate their sequences with their roles within their environments. …

… Leveraging decades of technological development, dozens of reference genomes and thousands of resequenced sorghum varieties, a resource for breeders and … high-quality reference genomes. By cataloguing a genome sequence for a line of sorghum, reference genomes have …

… A group led by JGI scientists have made strides in improving … domesticate some 60 strains, inserting into them a genetic sequence that acts as a “landing pad.” Mouncey adds, “Once … different gene deletions in four gammaproteobacterial species, and then removing the editing machinery afterward …

… All participants and staff of JGI events are required to adhere to the …