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… how genes are regulated is like deciphering the complex wiring behind a city’s power grid. Just as the flow … Now, with improvements to DNA Affinity Purification Sequencing (DAP-seq), these barriers are falling. As  … conservation; and integration with single-cell RNA sequencing reveals how transcription factors control gene …

… The 11th cohort of JGI-UC Merced interns pick highlights from their … other settings. Being an intern here has allowed me to make connections with the top of the top scientists in their … Nandita Nath & W. Berkeley Kauffman Project: “ 16s Sequencing of Barcoded Microbial Genomes ” Morgan Lavenstein …

… from Antarctica to Africa to global oceans. Through the Community Science Program of the U.S. Department of Energy … world’s oceans, found in a wide range of morphologies and ecologies. Diatoms, Bowler’s proposal noted, are believed … efforts appear to be redistributing water availability. By sequencing the millet rhizosphere and endosphere communities …

… Sequencing technology has changed dramatically over the … it possible for researchers to get a close look at more ecosystems and organisms than ever before. In 2006, the JGI … To meet this “ data tsunami ,” as Kathy Yelick of the Computing Sciences Area at Lawrence Berkeley National …

… Microbes drive critical ecosystem functions and affect global nutrient cycling, however they do so under strong constraints exerted by viruses. Research in the viral genomics group aims at improving our collective understanding of ecological and evolutionary …

…   To understand virus-host dynamics, computation helps fill in what cultivation can’t. The … do. It must be a specific host the virus has adapted to commandeer. For bacteriophage viruses, these hosts are microbes like bacteria, not humans. With metagenomic sequencing, researchers have found more of these viruses …

… a number of notable achievements that showcase our collaborations and capabilities to enable great science that … bacterium from a single cell. Several years later, the continuing single cell sequencing collaboration between the JGI and Bigelow Lab led …

… of California, Berkeley used a multi-omics approach to reconstruct and model gene regulatory pathways used by the … is the model organism for filamentous fungi, all of which contain a wide array of plant cell-wall degrading enzymes … and optimized by Ronan O’Malley, who leads the JGI’s Sequencing Technologies group. DAP-seq allowed the team to …