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Synthetic Biology Informatics Group
… gRNA-SeqRET , an organism-agnostic CRISPR gRNA design tool BOOST , which provides a suite of tools to automate sequence design for assembly by Gibson, Yeast … For further details, please reach out to the Group Lead …
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IMG Webinar Series
… Find a series of webinars related to our Integrated Microbial Genomics & Microbiomes portal. …
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Ian Blaby
… design and assembly, strain engineering and bioinformatic tool development/data analysis for synthetic biology and functional genomics. Prior to joining the JGI, he was a group lead at Brookhaven National Laboratory where he focused on functional genomics of phototrophs. …
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Busting the Unbreakable Lignin
… components   The Science There are three main ingredients to tackle when it comes to breaking down a plant for energy: … use of cellulose and hemicellulose is well-established: Across all life forms and with little exception, organisms … wasn’t quite accurate, and maybe anaerobic fungi living in soils or the guts of livestock were more capable than …
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Offerings & Capabilities
… Technologies department is   ensuring users have access to cutting-edge capabilities to help advance their science by generating data in three … rely on a multifaceted combination of genomic, transcriptomic, proteomic, phenotypic, metabolomic, imaging, sensor, …
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Mike Sneddon
… annotation pipelines that support JGI’s portals, tools, and the DOE’s emerging AI-enabled capabilities for … and AI for large-scale genomics and lab informatics. Prior to joining JGI in late 2025, he served as Director of Scientific Computing at Predicine, an NGS-based …
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User Support Analysis Group
… with main focus areas being genome variation, transcriptomics and epigenomics. Our work varies in scope from the development of highly customized analysis workflows for new product types, to the development of automated analysis pipelines for …
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Honey Bee Gut Microbiota Divvy Up Dinner
… bee gut microbes have a division of labor when it comes to metabolizing complex polysaccharides. Honey bees are … But scientists have wondered exactly how the microbial community carries out its helpful metabolism: … — the pectin and hemicellulose — are digested further along: first, the pectin, mainly by  Gilliamella ; then the …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… the earth, but most species do not grow easily in the lab. To access the genomes of uncultured  microbes , scientists usually employ two different methods; shotgun metagenomic sequencing and … together, they found most bacterial genomes from water and soil communities were at least 80% complete when studied …
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JGI@25: The Little Alga That Could
… that showcase our collaborations and capabilities to enable great science that will help solve energy and … Rokhsar, head of the JGI’s Computational Biology Program, along with JGI Computational Scientist Simon Prochnik, Arthur … sequences have been cited in almost one-fourth (23.8%) of publications focused on that specific algae. The reference …
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JGIota: A Tool to Find the Nomadic Genes that Help Microbes Adapt - geNomad
… A quick snippet on Antonio Camargo and Simon Roux, a few of the JGI researchers … behind software that finds plasmids and viruses within microbial genomes. As mobile genetic elements like viruses … DNA, they can affect how microbes cycle nutrients and adapt to climate change. …
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Bioenergy sorghum stem density increases threefold following internode elongation due to continued accumulation of lignified cell walls and complex regulation of genes involved in cell wall biosynthesis
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