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Workforce Development & Education Outreach
… JGI’s role in enabling complex biological and environmental systems research.  …
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iPHoP: A Matchmaker for Phages and their Hosts
… workflow, then uses a machine-learning model to give its integrated prediction a confidence score. The result is a … led by scientists at the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility at … used 1,870 known virus-host pairs to generate a matrix of data points.  Applied to 216,015 high-quality virus …
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Complete Genome of Oil-Rich Alga Reveals Ideal Platform for Bioengineering
… Streamlined genome with precise gene targeting transforms oil-producing … products.    The Science Scientists have fully decoded the genome of an oil-producing green alga, and demonstrated … applications. Engineers could manipulate these natural systems to tune gene activity without permanently altering …
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Celebrating a Decade of Science through the JGI-UC Merced Genomics Internship Program
… of the flagship internship program between the DOE Joint Genome Institute (JGI) and University of California (UC), … Internship co-founder Axel Visel and UC Merced Quantitative Systems Biology professor Carolin Frank reflected on the … and a teaching assistant for the UC Merced Quantitative and Systems Biology department.   Jonelle Basso , a JGI research …
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2021 JGI Proposal Call Brings New Investigators into Community Science Program
… (CSP) call of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … call recommended including plans to analyze and distribute data through the  DOE Systems Knowledgebase (KBase) , a free, open source data … characterization and cleanup. The JGI provides integrated high-throughput sequencing and computational …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… bacteria, archaea and fungi. We thought this kind of analysis would provide a framework for the evolution of this … as well as the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … Facility located at Berkeley Lab. In addition to providing metagenome mining for computational analysis of the AT …
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Engagement Webinar: How to Successfully Apply for a CSP Proposal
… to make sure the goals, experimental design, and plan for data utilization are clear. Contact JGI staff for feedback … a proposal. Describe in detail what you will do with the data! Ideally, you or someone on your team will have … how KBase (www.kbase.us) can support biological data analysis. It is a free, open source analytics platform …
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Better Genome Editing for Bioenergy
… included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User … a team of researchers sought to disrupt every gene in the genome with CRISPR-Cas9 in order to interrogate each one’s … a pool of sgRNA sequences: six for every gene in the genome. The JGI  DNA Synthesis Science team synthesized …
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Transcriptome analysis of Aspergillus niger xlnR and xkiA mutants grown on corn Stover and soybean hulls reveals a highly complex regulatory network
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Metabolic analysis of the soil microbe Dechloromonas aromatica str. RCB: indications of a surprisingly complex life-style and cryptic anaerobic pathways for aromatic degradation
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Genome Sequence of the Mesophilic Thermotogales Bacterium Mesotoga prima MesG1.Ag.4.2 Reveals the Largest Thermotogales Genome To Date
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Hiroshi Otani
… Since joining the DOE Joint Genome Institute in 2016, Dr. Otani has been studying … 2023 Feb 17;50(1):kuad005. Otani H, Udwary DW, Mouncey NJ. Comparative and pangenomic analysis of the genus Streptomyces. Sci Rep. 2022 Nov … Publications …
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