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… CheckV can help researchers assess virus sequence fragments and data … (metagenomes). However, the quality and completeness of metagenome-assembled virus sequences vary widely. In a … The work conducted by the U.S. Department of Energy Joint Genome Institute is supported by the Office …

… A team has optimized a crucial part of CRISPR-Cas9 … Cas9 needs guide RNA to lead it to the correct sequence to snip — but not all guides are effective. To … approach: CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, …

… A workflow for capturing the genetic make-up of specific … The Impact Despite great strides in generating genome sequences for members of the microbial world through bulk … The work conducted by the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …

… A genetic architecture that is characteristic of the sex … first time, the sex chromosomes of shrub willow have been sequenced with sufficient resolution to analyze their … This work was supported by the NSF Dimensions of Biodiversity Program (DEB-1542509 to S.D., DEB-1542486 to …

… Leveraging decades of technological development, dozens of reference genomes and thousands of resequenced sorghum varieties, a resource for breeders and … high-quality reference genomes. By cataloguing a genome sequence for a line of sorghum, reference genomes have …

… A new approach for improving functional annotation in fungal genomes. The Science In a proof-of-concept study, researchers demonstrated that a new … then used a series of random insertions of a foreign DNA sequence to generate a huge pool of mutants, each containing …

… The Environmental Molecular Sciences Laboratory (EMSL) and the Joint Genome Institute (JGI) provide access to a variety of tools that leverage stable isotopes to measure carbon and … The more the better. We want to put at least a microgram of DNA in the tube so you’d need at least 2 micrograms in …