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… Cas14 proteins discovered from JGI’s IMG/M database and biochemically … The results yielded several CRISPR-Cas systems, and based on several experiments conducted by Doudna’s lab at UC … to develop a Cas14-DETECTR that allows for CRISPR-based detection of ssDNA pathogens. With few exceptions, the Cas14 …

… A workflow for capturing the genetic make-up of specific uncultivated microbes … of the microbial world through bulk community sequencing (metagenomics) and single-cell genomics, the vast majority of … signal amplification provided by HCR-FISH is critical for detection. Once cells are labeled with HCR-FISH, they can be …

… DAN: You’re listening to the US. .Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … the system. [ Go here to learn more about Cameron Currie’s metagenomics research, enabled in part by JGI’s Community … the laboratory of Jo Handelsman at the University of Wisconsin-Madison. You can find the podcast on Apple , Google , …

… Dr. Kyrpides joined the DOE Joint Genome Institute in 2004 to lead the Genome Biology Program and the development of the comparative analysis platforms for microbial genomes and metagenomes (IMG). He became the Metagenomics Program head in 2010 and has the combined …

… for Education and Discovery  (Myco-Ed) is a Course-Based Undergraduate Research Experience (CURE) that consists of coordinated hands-on experiments across fungal biology teaching … Beyond providing a scalable solution for production of high-quality fungal reference genomes, this program is an …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a … and offered a way for researchers to study the planet’s microbial diversity, much of which remains unknown and … of the tree of life. Used in tandem over the years, metagenomics and single cell genomics have afforded JGI …

… is not exclusively for Euryarchaeota. Atmospheric levels of methane, a potent greenhouse gas, regulate Earth’s climate. Most methane is produced in environments without oxygen through a process called … to  Euryarchaeota .  Finding Methane-Making Microbes with Metagenomics  By leveraging metagenomics to sample the …