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Microbes drive critical ecosystem functions and affect global nutrient cycling, however they do so under …   19 , 407 Berg, M. et al. (2021) Host population diversity as a driver of viral infection cycle in wild populations of … abundant ocean viruses.  Nature . 537:689-93. … Selected Publications … For further information contact the Group …

… including single-cell and spatial transcriptomics barcode-based genetics (RB-TnSeq), and computational genomics to … myriad of bacterial strains, whereby they can modulate host metabolism, gene expression and phenotype. We have recently … of plant/environmental responses … Selected Publications … Research Team Alumni … For further details, …

… … DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger Linington, from … institutions in developing nations to do natural products based drug discovery, predominantly in diseases of … She talks to lots of great scientists outside of secondary metabolism, and if you like what we’re doing here, you’ll …

… looked across many organisms to see that aminotransferase enzymes have evolved mix-and-match characteristics — … molecules. So they’re involved anytime you make an amine-based molecule — a very critical role,” he said. These … many organisms function, they have a sense of why nitrogen metabolisms can be so varied.  As evolution has progressed, …

The Secondary Metabolism Collaboratory encourages user engagement. The … secondary metabolites are produced by groups of genes known as biosynthetic gene clusters (BGCs.) As reported in the … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence …

… in changing conditions. The products of photosynthesis are easy to point out. Plants, algae and cyanobacteria create the … and her team hypothesized that DUF2470 was key to iron metabolism, and renamed it to Domain Related to Iron, or DRI … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s …