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Doubling Down on Known Protein Families
… online Oct. 11, 2023 in  Nature highlights the vast array of functional diversity of microbes through a novel approach to … Research Center  Alexander Fleming. “This was a massive analysis of 1.3 billion proteins with massively parallel … integrated high-throughput sequencing and computational analysis that enable systems-based scientific approaches to …
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Comparative transcriptomics as a guide to natural product discovery and biosynthetic gene cluster functionality
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… with the HudsonAlpha Institute for Biotechnology.   Publications Grimwood, J., Gordon, L., Olsen, A. et al. The … J., Martin, J., Terry, A. et al. The DNA sequence and comparative analysis of human chromosome 5. Nature. 431, 268–274 (2004). …
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Who We Are
…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national … at Lawrence Berkeley National Laboratory. The JGI consists of 225 researchers and support staff in the Integrative … organisms. We provide access to large-scale datasets and analysis tools for genomes, metagenomes, and metabolomics …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant under … metabolic switches identified are shared across hundreds of related species, meaning these insights are potentially … bioproducts. This study offers a template — integrative analysis of multiple omics data from various environments — …
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Game On: High School Students Drive Everglades Metagenomics Study
… In late June, Kathleen Lail, a member of JGI’s Sample Management Group, attended a conference in … Genomes & Microbiomes (IMG/M) portal for their sample analysis.  The class had to sift through over 55 billion … and organic carbon concentration. From Field Studies to Publication Together as a class, the students learned about …
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Comparative analysis of carboxysome shell proteins
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Comparative analysis of GT14/GT14-like gene family in Arabidopsis, Oryza, Populus, Sorghum and Vitis
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Comparative analysis of the transcriptomes of Populus trichocarpa and Arabidopsis thaliana suggests extensive evolution of gene expression regulation in angiosperms
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John Vogel
… Dr. Vogel joined JGI in 2014 to establish a plant functional genomics program. Prior to this, he served as a … mutant collections, transformation technology, epigenetic analysis techniques) and utilizing these resources to … with their microbiomes. In addition, his group conducts comparative genomic research to understand the evolutionary …
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Phylogenomic analysis of polyketide synthase-encoding genes in Trichoderma
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Data Ecosystem
… The JGI is leveraging its current partnerships to offer new capabilities and resources to users through a BER … is discoverable and accessible. Linking the resources of powerful institutions like the JGI, KBase, NCBI, NMDC, … access to diverse datasets that deepen our understanding of how organisms interact with each other and with their …
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