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Natural Prodcast Episode 22: Alison Narayan
… recorded at the Society for Industrial Microbiology and Biotechnology (SIMB) Natural Products meeting earlier this … can it actually turn over? ALISON NARAYAN: So that’s an excellent question. I think that we need enzymes with good … that afternoon. Who knows? I mean, things– just the technology is evolving so quickly that enables this area of …
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Streamlining Regulon Identification in Bacteria
… RIViT-seq technology could speed up associating transcription factors … one type of RNA polymerase responsible for each gene. These bacterial RNA polymerases are made up of a core enzyme … factors and even other organisms can fuel a deeper understanding of these transcriptional regulatory networks. …
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Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
… threads in the mix. But in the Petri dish, the thin vermicelli-like threads floating delicately above the leaf debris are revealed to be single bacterial cells, visible to the naked eye. The unusual size … fundamental, creative research projects to advance our understanding of the natural world,” added Sara Bender of …
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Programs & Platform Leads
… to support BER's mission of achieving a predictive understanding of complex biological, earth, and …
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Applying Viral Genomics Expertise to Understanding the Human Virome
… collaborated with global researchers on projects related to understanding how the interactions between viruses and their … of metagenome-assembled viral genomes ( Nature Biotechnology , 2021), geNomad , a tool for identifying mobile genetic elements ( Nature Biotechnology , 2024), and iPHoP , an integrated machine …
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Rapid whole-genome mutational profiling using next-generation sequencing technologies
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… are now getting more complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but most species … with the JGI. Working together, they found most bacterial genomes from water and soil communities were at …
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A Grass Model to Help Improve Giant Miscanthus
… of California, Berkeley and the HudsonAlpha Center for Biotechnology. Most plants are diploids with two copies of each … , another species of Miscanthus that was sequenced. Understanding the evolution of polyploidy, and how genomes …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and … select to be engineered. “Piloting access to this emerging technology with JGI users will enable us to assess CRAGE’s … Newscenter story and this piece in  Current Opinion in Biotechnology . Now, CRAGE is being applied to other synthetic …
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Small cells with big secrets
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Biotechnological Innovations through Fungi
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Fungus Fuels Tree Growth
… matter, or as an endophyte, living between a plant’s root cells. The fungus is almost always found among and within … interest to the U.S. Department of Energy (DOE). By better understanding how poplar responds to its intimate … noting they increased expression of genes involved in signaling of gibberellin, one of the best-known plant growth …
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