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The Integrative Genomics Building (IGB) seen above is home to the DOE … 39,870 projects in FY24 We generated 871 Terabases of sequence We synthesized 9.7 Megabases of DNA We processed … scaled DNA-affinity purification sequencing (DAP-seq),  stable isotope probing (SIP) and omics, and we continue to …

Microbial cells infected by viruses undergo metabolic reprogramming. The Science If it looks like a duck … on the ecosystems can vary is a step toward developing more efficient predictive ecosystems models. Next, the …

Metagenomic datasets could help map out microbial diversity … genomic biodiversity. Using publicly available genome sequence data generated over the past three decades, their … group. “Turns out that despite all the genomes we've sequenced, we've only scratched the surface.” The study, …

The Community Science Program (CSP) provides the scientific community at large with access to high-throughput sequencing, synthesis, …

A team has optimized a crucial part of CRISPR-Cas9 … Cas9 needs guide RNA to lead it to the correct sequence to snip — but not all guides are effective. To … approach: CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, …

Schulz joined the DOE Joint Genome Institute in 2016 and is leading the New Lineages of Life Group. His research is … and eukaryotic microbes and viruses in environmental sequence data. Dr. Schulz employs multi-omics (metagenomics, …