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… call “known knowns” — that is, they are similar to genes with known function. Others are called ‘known … unknowns’ — that is, they are similar to previously known genes from isolate organisms, but we still aren’t sure of … into the uncharted territory of understanding the vast landscape of functional diversity, but we have also pushed …

… secondary metabolites are produced by groups of genes known as biosynthetic gene clusters (BGCs.) As … BGC sequences. Expansion of the SMC to include fungal, plant, viral, and metagenome data is currently underway. …

… assembly from Lake Mendota. In this episode: the software evolution that made metagenome assemblies like this possible. …

… are now getting more complete genomic results from single cells. The Science Studying the  genomes of microorganisms … methods; shotgun metagenomic sequencing and single-cell sequencing. For years, extracting single cells and then amplifying their DNA for genome sequencing …

… metagenomics. One approach uses fluorescence-activated cell sorting (FACS) to sort cells into several small pools before sequencing to recover … to link mobile elements such as plasmids to microbial host cells. In a separate article, research scientist Simon Roux, …

… Inc. in New Jersey and DSM Nutritional Products in Switzerland, and as Bioengineering and Bioprocessing R&D Director … include strategic planning and ensuring program excellence. The Director represents the JGI to its various … of Actinobacteria with 824 Isolate Reference Genomes. Cell Genomics 2: 100213 Nayfach S et al. 2021. A genomic …

… influence biogeochemical cycles in soils and sediments and plant-microbial interactions in crops. He has been a PI or … is an Assistant Professor in the Department of Ecology, Evolution and Marine Biology at UCSB, where she leads a research group investigating the physiology and evolution of marine aggregates and biofilms. She credits the …

… will be competitive. Q:  Can you elaborate on the single-cell genomics capabilities? A:  EMSL’s capabilities include laser capture microdissection, single cell sorting and nanoPOTs. The JGI’s single cell capabilities range from traditional single cell …