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How Filamentous Fungi Sense Food
… Tracing gene regulatory networks in the model fungus  Neurospora crassa . The Science A team led by researchers at the University of California, Berkeley … to reconstruct and model gene regulatory pathways used by the filamentous fungus  Neurospora crassa, and to …
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JGI Pitches 2022 Visiting Faculty Program Collaborations
… & Education department of Lawrence Berkeley National Laboratory (Berkeley Lab) hosted a pitch event promoting … for current faculty. Applying faculty members may invite up to two student participants from the faculty member’s home … for the DOE Systems Biology Knowledgebase (KBase) Ian Blaby for the JGI DNA Synthesis Platform Ben Bowen and …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… A group led by JGI scientists have made strides in improving and applying a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the … application could scale,” says Mouncey. The JGI team has already demonstrated CRAGE as a versatile engineering system …
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Yasuo Yoshikuni
… Science Program since 2015. The mission of this program is to harness the power of DNA synthesis, strain engineering, … and renewable chemicals, developing genome engineering tools for non-model organisms, modulating microbe-microbe … and plant-microbe interactions in various environments to improve crop yield, and developing a platform for …
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DAS Tool for Genome Reconstruction from Metagenomes
… Developing and validating an integrated approach to genome recovery from metagenomes. The Science Through the … binning algorithms, allowing them to reconstruct more near-complete genomes from soil metagenomes compared to … the efficacy of this approach would be greatly increased by having the ability to reconstruct complete genomes of …
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Emiley Eloe-Fadrosh
… Dr. Eloe-Fadrosh joined the JGI in 2014 to pursue her research interests in microbial ecology and … datasets from host-associated and environmental samples to identify and characterize genomic information from uncultivated microbes and viruses. Prior to joining the JGI, she was a Bioinformatics Program Fellow …
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Gene Expression: From On-Off Switch to Dial
… Scientists have developed a more nuanced library approach to tuning gene expression in metabolic pathways. Compared to … on, scientists can determine the level of gene expression by the gradations. The Impact Metabolic engineering could … characteristics in an organism. The experiment was led by Hal Alper, professor and associate chair at the …
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Integrating Experimentation with Data
… (JGI) and the Environmental Molecular Sciences Laboratory (EMSL) at their joint meeting! “Empowering Automated Laboratories: Integrating Experimentation with Data” … instructive workshops. The abstract submission deadline has passed.    … informatic tools at no cost. The JGI and EMSL are supported by the DOE's Biological and Environmental Research (BER) …
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An Integrated Dataset to Understand Ecosystem Interaction
… poplar trees and their microbial partners. The Science To help better understand how ecosystems work and how … to large ecosystem-level processes for the first time. By collecting data from 27 different poplar ( Populus … to a sustainable bioeconomy. Summary The 27 samples studied by researchers came from two environments: natural forests …
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Mapping Heat Resistance in Yeasts
… yeast Saccharomyces cerevisiae , allowing this species to grow better than its closest relative S. paradoxus at … Efforts such as the 1000 Fungal Genomics Project led by the DOE Joint Genome Institute (JGI), a DOE Office of … aim to improve our understanding of fungal diversity by sequencing genomes from across the fungal Tree of Life, …
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How to Target a Microbial Needle within a Community Haystack
… from complex environmental samples. The Science A team led by researchers at the Max Planck Institute (MPI) for Marine … Microbiology has developed, tested and deployed a pipeline to first target cells from communities of uncultivated … even more challenging. To overcome this hurdle, a team led by Bernhard Fuchs and his postdoctoral researcher Anissa …
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Axel Visel
… Institute in Hanover, Germany, where he developed novel tools for large-scale in situ gene expression analysis in multicellular organisms. During his postdoctoral training at Lawrence Berkeley National Laboratory, he developed and applied novel computational and …
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