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… A team has optimized a crucial part of CRISPR-Cas9 … tool that can help scientists engineer organisms for bioenergy applications. Cas9 needs guide RNA to lead it to the correct sequence to snip — but not all guides are effective. To … This work was supported by DOE Joint Genome Institute grant  CSP-503076 …

… Developing and validating an integrated approach to genome recovery … and improved upon a tool that combines existing DNA sequence binning algorithms, allowing them to reconstruct … a team of researchers has been working on improving methods for isolating and characterizing entire microbial genomes …

… Retracing how the dry rot Serpula lacrymans adapted to a new ecological habitat. The Science By comparing genetic information from similar organisms, researchers have gained … Serpula species, S. himantioides from Europe, that was sequenced and analyzed by the JGI. The researchers found …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable … challenges, characterizing viruses is a key step. For decades, though, many viruses have been somewhat … CheckV, assesses viral genomes, and grades their quality based on completeness. Along with expanding the viral …

… the diversity of white rot fungi in the genus Lentinula   The Science Shiitake mushrooms get their name from the … 60 existing sequences, this work expands the family tree for Lentinula. Within those samples, this study also tracks … genus diverged roughly 28 million years ago, when the largest mammal ever, Paraceratherium, still roamed central …