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gRNA-SeqRET: a universal tool for targeted and genome-scale gRNA design and sequence extraction for prokaryotes and eukaryotes
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Uncovering Sequence and Structural Characteristics of Fungal Expansin‐Related Proteins With Potential to Drive Substrate Targeting
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Draft genome sequence of Clostridium tetanomorphum DSM 4474T isolated from a septic wound
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A Sorghum Pangenome Opens More Doors to Discovery
… development, dozens of reference genomes and thousands of resequenced sorghum varieties, a resource for breeders and researchers to harness the traits that let this biomass powerhouse thrive. Within its genome, … high-quality reference genomes. By cataloguing a genome sequence for a line of sorghum, reference genomes have …
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JGI@25 RECAP: 2022 Annual Meeting features historical perspectives on JGI’s 25 years
… Their talks shed light on how the JGI was established, all that it has contributed, and what they’re excited about in … so there was quite a bit of resistance to use resources to sequence it,” Patrinos said. After many more meetings and … idea was to put together a ‘Best of the Best’ genome sequence list, which I found utterly frustrating and …
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A One-Stop Shop for Analyzing Algal Genomes
… data repositories of its kind, with an interactive browser that allows algal scientists and enthusiasts to look deep … algal genomes can be incredibly complex and difficult to sequence and understand. A team of researchers led by Algal … inquiry: it shows a full phylogenetic tree of more than 100 sequenced algal genomes — many sequenced by the JGI — so …
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Sulfate-Reducing Bacteria That Produce Exopolymers Thrive in the Calcifying Zone of a Hypersaline Cyanobacterial Mat
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Better Genome Editing for Bioenergy
… is a powerful, high-throughput gene-editing tool that can help scientists engineer organisms for bioenergy … Cas9 needs guide RNA to lead it to the correct sequence to snip — but not all guides are effective. To … approach: CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, …
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The Power of One, Amplified
… low diversity hot spring sediment sample. Their work showed that single cell genomics can add significant value to the … snippets of microbial genomes directly from environmental sequence data, by piecing each genome together from large mixtures of genomic sequences. A complementary approach to this is single cell …
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Microbial Genomics & Metagenomics (MGM) Workshop
… workflows for computational analysis and interpretation of sequence data. IMG/M is a web-based platform that provides access to the wealth of public microbiome sequence data and enables the user to analyze these data …
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Taking Stock of the Known and Unknown Microbial Space
… genomic biodiversity. Using publicly available genome sequence data generated over the past three decades, their … within the JGI’s Microbiome Data Science group. “Turns out that despite all the genomes we've sequenced, we've only scratched the surface.” The study, …
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Researching and Solving Real-World Problems with the 2023 JGI-UC Merced Interns
… communications, their schedules were filled with trainings that they later reported were incredibly valuable to their … mentor Bryce Foster, Benchmarking Bioinformatics Tools for Sequence Similarity Searching Morgan Lavenstein Bendall and … and Frederik Schulz, Structure Prediction to Annotate Novel Viruses: the Case of Polintoviruses Josue Duque and mentor …
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