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An Enzyme System to Help Catalyze Bioproduction of Plastic
… By characterizing the structure and function of a methylthio-alkane … reductase system, researchers could open avenues for using bacteria to produce ethylene and more.  Microbes excel … a specific enzyme, Methylthio-alkane Reductase (MAR) in host bacteria Rhodospirillum rubrum . Their work in Nature …
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Coordinating Environmental Genomics and Geochemistry Reveals Metabolic Transitions in a Hot Spring Ecosystem
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Jane Grimwood Named HudsonAlpha Genomics Chair
… Congratulations to Jane Grimwood, who has been appointed the Loretta Purdy Spencer Chair in Genomics at the … large-scale multi-institutional JGI projects and resulting publications that Grimwood contributed to include: A 2021 … As well as the seminal Human Genome Project DOE Chromosome publications: The DNA sequence and biology of human …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… A group led by JGI scientists have made strides in improving and applying a method that allows researchers … into the genome. “CRAGE is central to our ability to offer host-engineering for our users,” says JGI Director Nigel … have also harnessed CRAGE to create a plant-fertilizing microbiome. In work  reported in  Applied and Environmental …
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Metabolomics
… strengthens -omics technologies at the JGI by identifying the actual molecules present in an environment that influence system behavior.  Through this identification, … Find more details on the instrumentation we use and our methodology for metabolite … Read more about our submission guidelines, what you can expect from your results as well as our …
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Streamlining Regulon Identification in Bacteria
… RIViT-seq technology could speed up associating transcription factors with their target genes. The … that can be turned on or off by the same regulatory protein. Researchers demonstrated the efficacy and potential of regulon identification by in vitro transcription-sequencing (RIViT-seq) to facilitate …
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Supercomputing, MetaHipMer and the Mega Dataset of Lake Mendota
… Sequencing technology has changed dramatically over the last  … They may also provide a basic understanding of the roles microbiomes play in determining the behavior of the physical … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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GAL08, an Uncultivated Group of Acidobacteria, Is a Dominant Bacterial Clade in a Neutral Hot Spring
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Ecophysiology of an uncultivated lineage of Aigarchaeota from an oxic, hot spring filamentous ‘streamer’ community
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Relationships between fluid mixing, biodiversity, and chemosynthetic primary productivity in Yellowstone hot springs
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Distribution and abundance of tetraether lipid cyclization genes in terrestrial hot springs reflect pH
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Abundant and active community members respond to diel cycles in hot spring phototrophic mats
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