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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… Newly developed chemiluminescent biosensors shed light on how bacteria function and … colonization, which can affect pathogenic and symbiotic bacterial interactions with animals and plants, or cause … resonance energy transfer (BRET)-based biosensors. In general, CSL biosensors produce large signal changes, but …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… planet’s microbial diversity is immense, yet much of it remains unknown. For more than a decade, researchers around the … is only available for a fraction of extant actinobacterial diversity. The article adds to the compendium … resource, but also yielding and supporting many high-impact publications ,” emphasized Markus Göker, who managed the …
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Gene Expression: From On-Off Switch to Dial
… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more nuanced … Foundation, and the JGI Synthesis Program under FP00005685. In addition, M.D. acknowledges funding from a National … User Facility, is supported under Contract No. DE-AC02-05CH11231. …
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Partnerships: Myco-Ed
… Research Experience (CURE) that consists of coordinated hands-on experiments across fungal biology teaching … species.  Students collect fungi, sterilize tissue, isolate genes and more. The metadata then goes into iNaturalist. … ~50 lineages selected for sequencing 16 genomes released 20 members from 15 institutions 300+ students 800+ …
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Fungal & Algal Program
… to unlock their potential for bioenergy, environmental sustainability, and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates … The Fungal & Algal Program harnesses cutting-edge sequencing technologies and advanced genomic …
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Learning to Look
… Machine learning approach significantly expands inovirus … case, the machine “learned” to identify a certain type of bacterial viruses or phages called inoviruses, which are … termed “self-targeting,” and yet still survived. The persistence of these “self-targeting” inoviruses suggested …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… This single environmental trigger highlights efficiency for users … Streptomyces are nature's chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay … a drastic metabolic shift. The net effect is coordinated upregulation of energy production, biosynthetic precursor …
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Phylogeographic reconstruction of a bacterial species with high levels of lateral gene transfer
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Changes in ambient temperature are the prevailing cue in determining Brachypodium distachyon diurnal gene regulation
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Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet
… Survey of Setaria's natural diversity reveals seed dispersal in wild populations for the first time. For years, Elizabeth … of plants have resulted in a paper published October 5, 2020 , in Nature Biotechnology . Kellogg and her colleagues, … at Lawrence Berkeley National Laboratory (Berkeley Lab), generated genome sequences for nearly 600 green millet …
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How Filamentous Fungi Sense Food
… Tracing gene regulatory networks in the model fungus  Neurospora crassa . The Science A team … which is aimed at determining the activity, expression and regulation of protein-coding genes. This first paper … We acknowledge the use of deletion strains generated by Grant P01 GM-068087 “Functional Analysis of …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… A group led by JGI scientists have made strides in improving and applying a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and … domesticate some 60 strains, inserting into them a genetic sequence that acts as a “landing pad.” Mouncey adds, …
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