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The Expanding Universe of Methane Metabolisms in Archaea
… into an ancient metabolism. Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions of years ago, methane-producing archaea likely played a key … said. “Overall, these results show a striking case of how metabolic diversity can emerge from tinkering of a common …
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Genomic and proteomic biases inform metabolic engineering strategies for anaerobic fungi
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From Intern to Published Scientist: The Journey of a JGI-UC Merced Intern
… For many scientists, the culmination of their work into a written report that is published in a … current PhD student, reached this milestone with a recent publication in Molecular Biology and Evolution . “It’s my … what we strive for,” Visel said. Practical Applications for Fungi Wint began working on the project that culminated in …
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Industry Engagement Program
… As a National User Facility, the JGI serves more than 2,500 users that predominately come from the public sector: … joined the JGI in 2017, he brought with him 20 years of industry experience — and an opportunity to expand the JGI’s portfolio of user companies. Now the Department of Energy is uniting …
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Uncovering Novel Genomes from Earth’s Microbiomes
… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … not already been associated with a host – with 23,000 MAGs. Modeling A New Path for Metagenomics Researchers Building … designed for biologists and bioinformaticians, developed metabolic models for thousands of MAGs. The models are now …
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Metabolic characterization of anaerobic fungi provides a path forward for bioprocessing of crude lignocellulose
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Natural Prodcast Episode 20: Brian Bachmann
… DAN UDWARY: Hey everyone and welcome back to a new session of Natural Prodcast. I’ve got two things I wanted to tell … went on to work at a groundbreaking company in the early 2000s called Ecopia, which was a very early genome mining … to merge with the synthetic biology community, with the metabolic engineering community because the skill sets are …
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A Community Resource for Secondary Metabolite Researchers
… user engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most … growth and reproduction—most organisms produce a set of "secondary metabolites," chemical compounds that often … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence …
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Hyperdiverse, bioactive, and interaction-specific metabolites produced only in co-culture suggest diverse competitors may fuel secondary metabolism of xylarialean fungi.
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From Competition to Cooperation
… Tracking evolution of symbiotic lifestyles across multiple fungal lineages. The … had ever been done before to look at how multiple forest fungi have independently evolved to establish symbiotic … genomes of symbiotic species available: 73 saprotrophs and 62 mycorrhizal species. The 62 mycorrhizal species include 29 …
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Separation of life stages within anaerobic fungi (Neocallimastigomycota) highlights differences in global transcription and metabolism
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Workforce Development & Education Outreach
… Outreach at JGI takes many forms: We offer internship opportunities through working directly with … Overall, our aim is to inspire students and established professionals to explore opportunities in STEM by providing … learning opportunities and ultimately, an understanding of the JGI’s role in enabling complex biological and …
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