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… and scientists of secondary metabolism. Welcome back for our second season of Natural Prodcast. This first … but also those molecules that mediate a well functioning ecosystem and environment and earth. So yeah, it’s like these … of genes that it searches for and uses a rule-based system that classifies the things that it finds into which …

… of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes … quantity and quality has been the rate-limiting step for many projects at the JGI. The quality of the starting … sequencing workflows and provide guidance as to how to perform sample QC prior to shipment: Importance of Sample QC …

National Laboratory. The JGI consists of around 280 researchers and support staff in the Integrative Genomics Building in Berkeley, California.  Our location at the IGB fosters team science and … collaboration with partner organizations such as the DOE Systems Biology Knowledgebase and the National Microbiome …

I wanted to tell you about in this introduction. First and foremost, our interview this week is with Professor Brian … and using engineered biosynthetic pathways and enzyme systems to do synthetic analoging of some really complex … buy– there wasn’t a encyclopedia of enzymes at Aldridge that I could use to buy green uricase or “Wittig-ase” or …

Meta-omics datasets show that CRISPR-Cas systems determine mutualism or parasitism between some … how these hosts and hitchhikers coexist is key for understanding their impact on wider ecosystems, but … harbored self-targeting CRISPR systems, metabolic modeling showed that  Ca . Huberiarchaeum would help fill in …

… not good at that, you guys. I’m trying really hard just for you. And the JGI Comms team. But mostly you. Anyway…I’m … I'm older, but-- [LAUGHS] I feel like a lot of people hedge their way into natural products by starting out in … can turn on the natural product, say clusters or expression systems so that-- BETSY PARKINSON: Exactly. DAN: --you get …

… work and outline roles and responsibilities resulting in a formal Statement of Work (SOW). All work performed at the JGI is initiated via the Work Initiation … Investigator Providing a general orientation to JGI systems to Investigators Preparation of formal Statement of …

… welcome, Nadine. ALISON TAKEMURA: What is the big picture for you in your lab? NADINE ZIEMERT: Big picture, I want to … where– I know you really dug into the evolution on that system. Did that affect the work that you’re doing now? … mining. We started to build the tools for natural product researchers that easily can identify secondary metabolite …