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Secondary Metabolites Program
…   The JGI’s Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, … in defense, nutrient acquisition and communication. Studying how these compounds are biosynthesized and their … The Secondary Metabolites Program targets the vast and …
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Mining Metagenomes for Cas Proteins
… at UC Berkeley and the Innovative Genomics Institute.  The Science Researchers report the discovery of miniature … to accurately edit genomes (that is, repair gene mutations, and either delete or add genes in a precise fashion) … author Lucas Harrington was a graduate student from study senior author Jennifer Doudna’s lab, and he worked …
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JGI Portals
… new algorithms, models and tools in support of DOE mission priorities. Data discoverability and accessibility are … from a single investment will be reused for further science.  Notices Data Portal files will be inaccessible … July 22–July 24 for computing upgrades . We regret any inconvenience. Effective July 27, 2026, the JGI will move to a …
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Frequently Asked Questions: Proposal Submission
… See below for a list of Frequently Asked Questions about our proposal submission process. You can review successful letters of intent and submissions at the bottom of the page.  … Review the list of open calls ; click on the call link to see specific details including project …
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Finding the Fermenters
… an interactive browser that allows other researchers to study the genomes and predict the metabolic abilities of … One test was to predict traits of more than 400 cultured rumen prokaryotes from the  Hungate1000 project . They also used the tool to predict possible functions from 733 metagenome-assembled rumen genomes. Finally, they used the …
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Secrets of the Needles: What Microbes do on Conifer Leaves
… Novel study looks at microbiomes in aerial surfaces of plants and their roles in plant health and environmental processes. The Science In a recent Microbiome paper … the analysis of mobile genetic elements across all of the metagenomes. Learn more about her time at the JGI here . …
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Comparative analyses of foregut and hindgut bacterial communities in hoatzins and cows
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Engagement Webinar: Utilizing long-read sequencing for metagenomics and DNA modification detection
… This webinar focused on how the JGI employs single-molecule, long-read DNA … applied to DNA methylation analysis as well as improving metagenome assemblies. Q&A from the Webinar: Input & … weight DNA) is an important factor as well for PacBio metagenomes. Q: How many PacBio metagenomes can I submit?  …
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Axel Visel
… the DOE Joint Genome Institute in 2010. As the Deputy for Science Programs, he focuses on the development and implementation of strategic initiatives at the JGI. Dr. Visel received … Axel Visel is the JGI's Deputy for Science Programs. Click to learn more about our seven …
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Synthetic Biology Lab
… Biology lab is divided into a DNA synthesis production group and a synthetic biology applications group. The DNA synthesis and assembly group: Our … including PacBio and Illumina.  The synthetic biology user science group: The applications group is focus on developing …
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Mining New Frontiers: The Critical Minerals and Materials Joint Call
… to request the capabilities and expertise of both national user facilities in one research proposal.  Submit research proposals  here that integrate genomics with nanoscale science, accelerating discoveries and developing … capabilities is free. The JGI supports remote users. Users conduct experiments in their own labs or collect field …
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JGI@25: Fueling Investigation into Methane-Making Microbes
… In honor of the JGI's 25th anniversary in 2022, we have … specifically, from the methane-making microbes within their rumen. There is another climate-minded reason for studying rumen: Livestock live off plant matter, and their …
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