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Viruses Reprogram Cells into Different Virocells
Microbial cells infected by viruses undergo metabolic reprogramming. The Science If it looks like … outcomes of these infections can affect the interactions within their ecosystems. Summary Microbes drive the energy … For this project, RNA sequencing was done by the JGI, and proteomics and metabolomics analysis and microscopy at EMSL. …
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Dan Rokhsar
… and analysis of three human chromosomes. After successful completion of the human genome project, Professor Dr. Rokhsar ’s team has continued to develop computational methods applicable to the diverse … He currently leads the JGI’s Computational Genomics group, and is past lead of the Eukaryotic Genome Program …
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NeLLi — Symposium on New Lineages of Life
Genome Institute hosted the hybrid “NeLLi 2023 Symposium” delving into the most recent expansions of the Tree of Life … and single-cell sequence data have provided a means to access novel microbial lineages, leading to a new …   Laura Hug , University of Waterloo Fabien Burki , Uppsala University Rebecca Batstone , McMaster University …
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Hiroshi Otani
Since joining the DOE Joint Genome Institute in 2016, Dr. … actinomycetes. His research activity is focused on developing and implementing new technologies and … Characterization of p-hydroxycinnamate catabolism in a soil Actinobacterium. J. Bacteriol. 196, 4293-4303. Otani, …
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Eelgrass Proves to Be Much Younger Than We Thought
… that figure is likely closer to a mere 250,000 years — with many key colonization events in the Atlantic ocean … one of the largest carbon sinks in the ocean — occupying just 0.2% of the ocean floor, these meadows are … in various locations.  One group investigated changes in protein sequences, while others analyzed single point …
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Finding the Fermenters
… to convert food into energy. However, in environments with little or no oxygen, life had found other ways to … Research (BER) program to enable scientific discovery in support of the DOE mission. Fermentative metabolism occurs in … organisms on the list. They also searched IMG/M for all protein-coding genes belonging to each genome. The final …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
… scale to produce biofuels . Since one of the challenges of developing alternative fuels from plants is the high cost … — and rumen microbes are no exception. Back in 2011, JGI-supported researchers published a paper in the journal … scientists to study microorganisms that can’t be cultured by analyzing and then extrapolating data obtained from …
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Kjiersten Fagnan
Kjiersten Fagnan began working with JGI in 2012 as a NERSC bioinformatics computing … Lead with a focus on adapting JGI workloads to run on supercomputing hardware and worked closely with staff to understand the data-intensive nature of JGI workloads. Dr. …
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Yasuo Yoshikuni
… discovery and applications. This program has supported over 250 projects since it started. At the JGI, Dr. … … Shen et al., Mitochondrial ATP generation is more proteome efficient than glycolysis., Nature Chemical Biology … , 2023 Wu et al. Structural characterization of a soil viral auxiliary metabolic gene product - a functional …
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New Vision, New Mission, New Plan: The JGI’s Next Five Years
… opportunities for the global research community. The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) has … .) This plan aligns the DOE Office of Science user facility with broader national efforts to promote and stimulate a … for a sustainable bioeconomy. To accomplish this vision, an updated mission statement for the user facility sets out to …
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