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An Automated Tool for Assessing Virus Data Quality
… fragments and data quality. The Science Through advances in sequencing technologies and computational approaches, … perform functional assessment, host prediction, and phylogenetic analysis. The development of CheckV helps … these sequences may be tainted by the presence of non-viral genes. Up to this point, there has been a lack of fast and …
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Exploring the Diversity of the American Prairie’s Switchgrass
… switchgrass ( Panicum virgatum ) has long been a tantalizing potential biofuel feedstock. But switchgrass has a complex genome and, as a species, encompasses dizzying diversity. So, a team of scientists made an ambitious … traits — height, biomass, hardiness to cold, etc. — to its genes. The undertaking took shovels, trucks — and more than …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
In honor of the JGI's 25th anniversary in 2022, we have … contains about 6% of the human genome . They discovered genes linked to conditions such as cardiovascular disease, … about 2% of the human genome. They were interested in genes involved in repair of DNA damage, and those associated …
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JGIota: Looking Back at How Cow Rumen Samples Landed on a Syllabus
Back in 2011, JGI-supported researchers published a paper in the journal Science . It detailed how they’d used metagenomics to identify over 27,000 microbial genes. The data from that study is now used across …
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JGI@25: Expanding Metagenomics to Capture Viral Diversity
In honor of the JGI's 25th anniversary in 2022, we have … and a specific microbial host to replicate. Sequencing genetic material directly from samples sidesteps these … key aspect of viruses in the environment — their sheer genetic diversity. As pioneers of this field, the JGI has …
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JGI@25: Studying Sorghum’s Survival Skills
In honor of the JGI's 25th anniversary in 2022, we have … each variety stores sugars and sequesters carbon. 2015: Epigenetic Control of Drought Tolerance in Sorghum (EPICON) … over 50 other diverse sorghum genomes. Deep sequencing and genetic linkage analysis improve the genome’s accuracy, and …
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JGI Announces 2023 Community Science Program Awardees
Program call of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility … This year’s annual CSP call had five areas of emphasis: genes to function, plant and algal functional genomics, …
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Help from Citrus’ Bitter, Hardier Cousin
… to disease-resistance that could prove fruitful for saving Citrus from greening disease. You’ve probably never … annotating and analyzing the genome in order to find the genetic traits responsible for  P. trifoliata ’s hardiness, … Fred Gmitter, a UF/IFAS professor of citrus breeding genetics and longtime JGI collaborator, are senior authors …
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
New studies show methanogenesis is not exclusively for Euryarchaeota. Atmospheric … gas, regulate Earth’s climate. Most methane is produced in environments without oxygen through a process called methanogenesis. Methanogenic microorganisms therefore play a …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… diversity of large and giant viruses. While the microbes in a single drop of water could outnumber a small city’s … more than 8,500 publicly available metagenome datasets generated from sampling sites around the world, including … expanded 10-fold from just 205 genomes, redefining the phylogenetic tree of giant viruses. Metabolic Reprogramming a …
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Toward More Efficient Artificial Photosynthesis
Chloroplast mimic a platform to capture and utilize carbon in a synthetic fixation cycle. The Science Chloroplasts are … carbon captured from the atmosphere in a process that generates energy. The MPI team ultimately aims to develop an … Functional Genomics call, the JGI synthesized library of genes that code for Enoyl-CoA Carboxylase/Reductase (ECR) …
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New Research Sheds Light on Diversity in the Deep Sea
Microbial communities living near hydrothermal deep-sea vents hold vast potential for … conditions. They identified 511 new or recently discovered genera of bacteria and archaea. Many of the samples shared a high prevalence of genes involved in sulfur and nitrogen metabolism, as well as …
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