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Gut Fungi: Unexpected Source of Novel Chemicals
… and help them digest their last leafy meal. In their evolutionary history, these fungi branched off early from aerobic … and because anaerobic fungi can’t harness it, scientists long held that these fungi don’t have the energy to make complex compounds called …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… team  announced in  Nature Microbiology an important addition to the synthetic biologist’s toolkit: a technique for  c … Mouncey. Using CRAGE, JGI has established a portfolio of microbial hosts that users can select to be engineered. … PLOS One , engineering different gene deletions in four gammaproteobacterial species, and then removing the editing …
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JGI@25: The Little Alga That Could
… In honor of the JGI's 25th anniversary in 2022, we have … sequences have been cited in almost one-fourth (23.8%) of publications focused on that specific algae. The reference … genome is cited in roughly 10% of all since-released publications on green algae. “The Chlamy genome launched …
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How Maize Makes An Antibiotic Cocktail
… a family of compounds that protects it against infections — using surprisingly few enzymes. The Science Maize ( … corn variety and protect maize by fending off fungal and microbial infections. Scientists had assumed that maize synthesizes these … AFRI (1758976 to A.H. and E.S.) for sesquiterpenoids, National Science Foundation Plant-Biotic Interactions Program …
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Evolution of a Fungal Gene Expression Regulator
… analysis to date of the modified DNA base 5mC variations in fungi. The Science Changing an A, C, T or G in a … can lead to changes in protein structures and functions, but the DNA bases themselves can also be modified. The best-known example of a modified DNA base is a methylation of the base cytosine at the 5th position on its carbon …
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Jane Grimwood Named HudsonAlpha Genomics Chair
… Congratulations to Jane Grimwood, who has been appointed the … large-scale multi-institutional JGI projects and resulting publications that Grimwood contributed to include: A 2021 … As well as the seminal Human Genome Project DOE Chromosome publications: The DNA sequence and biology of human …
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Supporting Global Research into Actinomycetes
… word. The 500 species described within the group are responsible for roughly two-thirds of antibiotics, and a deeper … are also abundant in soil and can be used as biocontrol agents and to promote plant growth. It is the largest … and the focus of a  recent paper published in  Microbial Genomics .   “Studying actinomyces, especially …
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iPHoP: A Matchmaker for Phages and their Hosts
…   To understand virus-host dynamics, computation helps fill in what cultivation can’t. The Science At first, viruses are merely toolkits. … opens the possibility of using phages to engineer microbial communities. One day, these phages could boost … of Energy, Office of Science, Biological and Environmental Research, Early Career Research Program awarded …
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Complete genome sequence of Granulicella tundricola type strain MP5ACTX9T, an Acidobacteria from tundra soil
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Complete genome sequence of Granulicella mallensis type strain MP5ACTX8T, an acidobacterium from tundra soil
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Access to Rock Star Scientists
… Cole, Mo Kaze, Akshay Paropkari, Vicente Ramirez and Rhondene Wint had summer 2018 internships in Walnut Creek. The … JGI Mentors : Ben Cole & Axel Visel, Genomics of Plant-Microbial Interactions “The summer internship has further …     Mo Kaze, UC Merced JGI Mentor : Susannah Tringe, Microbial Systems Group “Everyone here is very kind and …
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You Can Move, But You Can’t Hide
… and spread from cell to cell. Two of the most common forms of MGEs are viruses and plasmids. They can be found … called geNomad identifies and classifies MGEs based upon their gene content and their genetic sequences. The … in soils and water. MGEs like viruses and plasmids drive microbial processes and evolution. This is because MGEs can …
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