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… enabled by the JGI DNA Synthesis Science Program. Fashioning DNA outside a cell is key to interrogating what genes … in the Synthetic Biology special issue, Modular cell-free expression plasmids to accelerate biological design in cells , … and her own as an early career researcher. “We were able to study hydrocarbon biosynthesis at a scale that would …

Analysis reveals cotton genome stability across global lineages . Come harvest time, the cotton fields look like … cotton genome ( G. raimondii ) several years ago. Studying the cotton genomes provides breeders with insights … United States, and is working to address some of the most pressing challenges of our time. For more information, …

Since joining the DOE Joint Genome Institute in 2016, Dr. Otani has been studying secondary metabolism in microbes, particularly … Characterization of p-hydroxycinnamate catabolism in a soil Actinobacterium. J. Bacteriol. 196, 4293-4303. Otani, …

Researchers looked across many organisms to see that aminotransferase enzymes have evolved mix-and-match … Facility located at Berkeley Lab. In addition to providing metagenome mining for computational analysis of the AT … around, regardless of malfunction or misplacement.  In studying this family of ATs, researchers found that these …

Pictured is a timelapse of the Integrative Genomics Building (IGB) seen above is home to the DOE Joint Genome Institute (JGI). Researchers from the DOE Systems …

… led by researchers at the University of Texas (UT) at Austin, the HudsonAlpha Institute for Biotechnology … outline the questions they asked – and answered – in the study that recently appeared in the Proceedings of the … ecological and evolutionary consequences. A previous study conducted by our research team surveying the genomic …

For the first time in several years, the DOE Joint Genome Institute hosted … Emerald Nash and mentor Jonelle Basso, Experimental Study of Root Colonization by Resident Phages of a Plant … Sonia Vargas and mentors Tomas Tyml and Frederik Schulz, Eukaryotes in Extreme Environments Theo Loreaux and mentors …

Maize produces a family of compounds that protects it against infections — using surprisingly few enzymes. The … maize. By deciphering the zealexin synthesis pathway, this study makes it possible to harness the protective function … in the ability make zealexins, and harnessed gene expression data from these lines to identify genes associated …

… has been head of the DNA Synthesis Science Program since 2015. The mission of this program is to harness the power of DNA synthesis, strain engineering, and biosystems design for … , 2023 Wu et al. Structural characterization of a soil viral auxiliary metabolic gene product - a functional …

A “bait and hook” single-cell genomic approach to bioprospecting. The Science … their functional roles in their community. This study shows how the function-driven, single-cell screen can … DNA synthesis and cloning, followed by protein in vitro expression and mass spectrometry-based enzyme activity assay. …

Chloroplast mimic a platform to capture and utilize carbon in a synthetic fixation cycle. The Science Chloroplasts are the factories in plant cells. Using photosynthesis, they take raw … can be further explored for novel functions. In the current study, the team combined the CETCH cycle with a …

New genomes highlight the diversity of white rot fungi in the genus Lentinula   The Science Shiitake mushrooms get their name from … the family tree for Lentinula. Within those samples, this study also tracks the enzymes these fungi use to break down …