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… A new approach for improving functional annotation in fungal genomes. The Science In a proof-of-concept study, researchers demonstrated that a new genetic mapping … species that have been separated for millions of years. The study highlights the genes that could be used to make other …

… Kaushal Sharma, one of five Antioch High School rising juniors who participated in internships at the DOE Joint Genome Institute this summer … his student’s contributions as reviewing close to 3,800 metagenomes to verify geographic locations and assign …

… complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful … attempt to put them back into the original genomes. These metagenome-assembled genomes (MAGs) that came from shotgun … together, they found most bacterial genomes from water and soil communities were at least 80% complete when studied …

… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more … optimization. Summary Life is all about balance. This study,  recently published in the  Proceedings of the … Foundation, and the JGI Synthesis Program under FP00005685. In addition, M.D. acknowledges funding from a National …

… gas, regulate Earth’s climate. Most methane is produced in environments without oxygen through a process called … confirmation bias, because it enables scientists to study how methanogenesis takes place in the context of the … They could just be switched off.” Yet, after extensive study, Hatzenpicher and his team were able to definitively …

… s ditched their flagella and other traits when migrating back to the ocean. The Science Scientists have … unique array of chemicals not typically found in oceans or soils.  A recent study published in  The ISME Journal     focused on a class … ) conducted by the U.S. Department of Energy Joint Genome Institute (https://ror.org/04xm1d337), a DOE …

… RIViT-seq technology could speed up associating transcription factors with their target genes. The … that control transcription. Summary Transcription in eukaryotes is handled by three distinct RNA polymerases; in … given sigma factor are inferred. Prior to this most recent study, only 12 sigma factors and 200 genes (or 209 sigma …

… By characterizing the structure and function of a methylthio-alkane … reductase system, researchers could open avenues for using bacteria to produce ethylene and more.  Microbes excel … innovation ecosystem. “At JGI, we’ve done the synthesis, metagenome mining, all the way from sequencing to functional …

… Do metabolic pathways from engineered yeasts still work in cell-free environments? … of sustainable chemical products,” said Jewett, one of the study’s senior authors. “But this has been done most … graduate student Blake Rasor. He and Yi, one of the study co-authors, have maintained a regular shipment …

… Sequence-based studies — from metagenomics to single-cell work — have quickly accelerated understanding of … and how sequencing and bioinformatics have sped up the study of giant viruses. The Impact In their existence as … reference genome, to sift for snippets of giant viruses in metagenomes. This has been useful in marine environments, …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements … to their economies. It also plays an important role in soil health through nitrogen-fixation and holds clues for …

… Earth and DNA are close to our JGI hearts, we’re highlighting genomic science research that feels especially relevant to living on a changing planet. Mo Kaze is a University of … and metabolism, work on which she is expanding with her study of microbes in California’s manmade water transport …