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JGI@25: Roots of a Mutualist Relationship
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements … at the JGI and the French National Institute for Agriculture, Food and Environment (INRAE). Today, there are …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… a more systematic picture through single-cell and metagenomic sequencing. A team co-led by Mária Džunková, … and archaeal cells — and detected the virus in 34 hosts or 26 percent of the single cells. Metagenomics sequencing then allowed the team to ask, for the …
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Exploring Phages at JGI
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Natural Prodcast Episode 3: The Primer, Part 3
… and listen to the first two parts ( part 1 is here and part 2 is here ) so you understand what’s happened so far in the … me to check her stat and she was absolutely correct. Since 2010 there have been eight new antibiotics added to the … from your cultures, but then you’re going to find another 20 or 30 secondary metabolism pathways that you didn’t even …
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Len Pennacchio
In 2003, Dr. Pennacchio joined the DOE Joint Genome Institute … Enhancers VISTA Cardiac Enhancer Browser ENCODE FaceBase … 2021-  NLM Board of Regents Working Group on “NIH … 2021-  Co-Chair, “Advances in Genome Biology & Technology- Agriculture” 2021-  Weill Neurohub Investigator 2020  …
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iPHoP: A Matchmaker for Phages and their Hosts
… these hosts are microbes like bacteria, not humans. With metagenomic sequencing, researchers have found more of these … pairs to generate a matrix of data points.  Applied to 216,015 high-quality virus sequences in the IMG/VR database, … such as terrestrial soil, having additional isolates and metagenomic datasets will strengthen future virus-host …
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Extracting the Secrets of Secondary Metabolites
… for a slew of vital products in biotechnology, medicine, agriculture, and other industries — yet there’s still so … in overcoming this obstacle when it hit the scene in 2019. Now, that power is poised to grow exponentially by … are produced and how to leverage their powers in agriculture, pharmaceuticals, biofuels and beyond.  … The …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and his team  announced in  … of stable, synthetic microbial communities to take advantage of their joint metabolisms. Because, together, microbes …
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Dealing with Drought: Uncovering Sorghum’s Secrets
… from the University of California (UC), Berkeley, UC Agriculture and Natural Resources (ANR), US Department of Agriculture P­­lant Gene Expression Center, Pacific … For that reason, its genome was sequenced by the JGI in 2009 and it is considered to be a Flagship Plant. By …
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Engagement Webinar: Harnessing JGI’s Metabolomics Capabilities
The JGI Engagement Webinar held November 5, 2020 (watch the  video below, captions are available) … see this  Metabolomics Data Analysis – Tips from Users page.  Q:  Is the metabolic study able to build a profile …
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A Shrubbier Version of Rubber
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Natural Prodcast Episode 2: The Primer, Part 2
… to the second episode of the Natural Prodcast. This is part 2 of our “primer” episode, so if you ended up here somehow … maybe obvious or notable. We are still in – not an early stage. I think we can identify most secondary metabolism … yeah. I mean, you might be producing things at different stages of growth or different signals from the environment …
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