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… between two genomes,  we use it to identify and classify bacteria and archaea as well as gain insights into the … R.A. et al. Cryptic inoviruses revealed as pervasive in bacteria and archaea across Earth’s biomes. Nat Microbiol 4 … A data discovery tool that is publicly available in the integrated microbial …

… target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory protein. … by in vitro transcription-sequencing (RIViT-seq) to facilitate the characterization of transcriptional … particularly sigma factors that initiate transcription in bacteria. Using this technology, which combines an in vitro …

… gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth yet … describe the functions of the biosynthetic gene clusters that produce them. The Impact Secondary metabolites are … pest control. Secondary metabolites are highly regulated in bacteria, making it difficult to identify which pathway …

… of biosynthetic gene clusters for novel secondary metabolites for multiple applications. The planet’s … and produce antibiotics. Still, the team estimates that genomic information is only available for a fraction of … resource, but also yielding and supporting many high-impact publications ,” emphasized Markus Göker, who managed the …

… User Facility, as well as a member of  its Secondary Metabolites research group . That group, led by JGI Director Nigel Mouncey, has launched … data and make publicly-visible comments. Its purpose is to facilitate open scientific discussions and connect users to …

… communities of algae with warm-adapted ones, a trend that threatens to destabilize the delicate marine food web … webs are microscopic photosynthesizing organisms called phytoplankton (from the Greek phyto for ‘plant’ and planktos … contribute to an estimated 50 percent of the world’s fixed carbon, altering the balance of eukaryotic and prokaryotic …

… The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most living … a set of "secondary metabolites," chemical compounds that often confer specialized capabilities that allow the … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence …

… years, has been to bring generalizable technologies to bacteria, yeasts and algae previously with little to no …