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DOE Metrics
… FY 2026 DOE Metrics Sequencing Quarter Total Bases (Trillions) Operating Hours Goal  Actual Total*   Actual % of Goal   Goal (hours)**   Actual Total   Actual % Goal   FY … the shelter-in-place. ††† Actual Operation = 69 days due to reduced lab activities related to the return-to-work plan in …
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Green Algae Reveal One mRNA Encodes Many Proteins
… Gene expression in eukaryotes was long held to be monocistronic – … a single protein. Recently reported in the Proceedings of the National Academy of Sciences , a team of researchers … examples of polycistronic expression – in which two or more genes are encoded on a single molecule of mRNA – in two …
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Gene Expression: From On-Off Switch to Dial
… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more nuanced … to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene … This work was funded by the Air Force Office of Scientific Research under Award No. …
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JGI@25: The Little Alga That Could
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … is a single-celled alga with a unique place in evolutionary history. Retaining ancestral features of both … sequences have been cited in almost one-fourth (23.8%) of publications focused on that specific algae. The reference …
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Industry Engagement Program
… Facility, the JGI serves more than 2,500 users that predominately come from the public sector: academic and government … joined the JGI in 2017, he brought with him 20 years of industry experience — and an opportunity to expand the … including User Facilities like the JGI, through its Genesis Mission. Launched in 2025, the initiative aims to …
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Insights into the red algae and eukaryotic evolution from the genome of Porphyra umbilicalis (Bangiophyceae, Rhodophyta)
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From Stress to Growth: The adaptive mechanisms of algae in changing Arctic waters
… P. psychrophila genes drive resilience when salinity fluctuates. The Science … ice in the Arctic has decreased by more than 30% in terms of quantity and thickness. Replacing older, thicker ice with … cell death.  Scientists then extracted RNA to analyze gene expression, to determine which genes are active under …
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Widespread polycistronic gene expression in green algae
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A One-Stop Shop for Analyzing Algal Genomes
… data portal allows anyone to freely investigate the genes of more than 100 algae. The Science Interested in the … algae, but many kinds of algae exist. During the course of evolution, algal organisms sprung up in almost all branches … where data are available, a user can also analyze gene expression from published experiments; study DNA …
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Making a Lichen Together
… For the first time, a team analyzes the transcriptomes of a lichen fungus and alga to understand their partnership … the microalga,  Asterochloris glomerata . To see how gene expression changes when living together versus apart, the … clonally. Yet its genome revealed that the alga has all the genes needed for meiosis, and thus can rapidly create …
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How to Submit Sequencing Samples
… Below is a brief description of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes instructions on accessing sample-level reports and … sample QC requirements and protocols Obtaining DNA and RNA of suitable quantity and quality has been the rate-limiting …
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DAP-seq Drives Robust Mapping of Gene Regulation
… Multi-species assays yield an unprecedented view of plant evolution and adaptation.    Understanding how … — and integrated these data with single-cell gene expression maps. Together, the scale of data enabled by … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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