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… quantities of DNA derived from individual environmental cells. The proof of principle study built off earlier … first closed and finished genome derived from an uncultured bacterial single cell – a symbiont of the green … waters. The top image on the left shows how, from a single bacterial cell (seen here in a glass capillary), researchers …

… as DNA affinity purification sequencing or DAP-seq. The technology was developed by Ronan O’Malley , who leads the … transcription factors to a genomic DNA library. “It’s an innovative way to rapidly capture the binding location for … “We thought about reconstructing gene regulatory networks, understanding where transcription factors bind in the …

Microbial cells infected by viruses undergo metabolic reprogramming. … approach to infecting and metabolically reprogramming the bacterial host, which was transformed into two very … models. Next, the researchers are working towards better understanding how nutrient availability, or lack thereof, …

JGI’s DNA synthesis and ‘omics capabilities to enhance understanding of gene and genome function, particularly …

… activities using phylogenomic driven approaches, and understanding the design principles for successfully … by combining combinatorial synthesis, high-throughput screening methodologies, and statistical frameworks for …

… extreme wildfires, more and more forests are under threat. Understanding which microbes in the soil persist after a … helpful bacteria, viruses and fungi. Overall, better understanding of a recovering soil microbiome provides a … samples, they reconstructed and examined over six hundred bacterial genomes — mainly actinobacteria, as well as …