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Natural Prodcast Episode 4: Nancy Keller
I enjoyed your talk today. It was another great example of probing fungi for natural products and finding new things. … fungi were transformed. So I wasn’t even thinking of molecular genetics of finding genes when I first started … the secondary metabolome, of fungi in inter-Kingdom interactions. So fungi, bacteria and their host. And I think …
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Natural Prodcast Episode 7: Ben Shen
… these natural products. So this gives you approximately a 6% successful drug discovery rate.   And this is 100 times … so-called golden age of antibiotic discovery in the 50s and 60s. And, from which, the majority of antibiotics was … we have here – all of them were collected before 2016, before that true enforcement of the Nagoya protocol. And …
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Synthesis
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Webinar: Introducing the BioSANS capability
The BioSANS instrument is at the Center for Structural Molecular Biology (CSMB) at Oak Ridge National Laboratory.   On March 2, 2021, the Environmental Molecular Sciences Laboratory hosted a webinar to showcase … (BioSANS) instrument when applying to the FY2022 EMSL-JGI FICUS call for proposals. Presentations from: Scott Lea, …
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Bacteria and Fungi Divvy Up the Work in Forest Floor
… in carbon and nitrogen cycling and forest floor ecosystem processes. Pinpointing the processes happening on and in … isolated and sequenced by scientists at the Environmental Molecular Sciences Laboratory (EMSL), a DOE Office of … the Facilities Integrating Collaborations for User Science (FICUS) initiative, which allows researchers to integrate the …
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Natural Prodcast Episode 6: Marc Chevrette
… metabolism.  DAN: Hi again, and welcome to Episode 6 of Natural Prodcast. What you’re going to get here is the … so we can train them to take the course back to their home institutions. ALISON: Oh, cool. So is that how it … angry with one another, and trying to unpack all of those interactions. You know, that’s what gets me excited. That’s …
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Comparative transcriptomics provides insights into molecular mechanisms of zinc tolerance in the ectomycorrhizal fungus Suillus luteus
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Natural Prodcast Episode 23: Aaron Puri
… chemistry of quorum sensing systems, specifically the acyl homoserine lactones.  If you listened to Betsy Parkinson’s … then we were using these probes to look at host pathogen interactions mostly with like enteric bacteria. And I really … Stable Isotopic Labeling . ACS Chem Biol. 2021 Aug 20;16(8):1332-1338. doi: 10.1021/acschembio.1c00329. …
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Rex Malmstrom
… microbes.  His group also handles the Stable Isotope Probing (SIP) Metagenomics pipeline  that reveals in situ … fluorescence activated cell sorting and non-standard molecular protocols.  Finally, his team utilizes new … stable isotope probing pipeline identifies cross-kingdom interactions in the hyphosphere of arbuscular mycorrhizal …
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Characterizing Communities: JGI Announces Latest CSP Portfolio
… relevant species. Another focus area was inter-organismal interactions, and two fungal proposals focus on symbiotic … physiology is impacted by these bacteria during mating processes. Kathryn Bushley of the University of Minnesota is … shrub’s presence, researchers hope to learn more about the mechanisms that allow the millet to thrive in drought …
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High-quality genome sequence of the radioresistant bacterium Deinococcus ficus KS 0460
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Cellular assays identify barriers impeding iron-sulfur enzyme activity in a non-native prokaryotic host
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