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Gene Expression: From On-Off Switch to Dial
… to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene … to the results of the sugar-related tests, they pinpointed multiple genes that were previously missed in knock-out … library synthesized by JGI was versatile enough for use in multiple applications. This proof-of-concept experiment …
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A Collaboration to Improve Plant Genome Annotations Across Species
… which specializes in genome improvement for plants. As part of that partnership, the JGI and HudsonAlpha researchers led … types, and analytical protocols that permit gene expression analysis across plants and add additional experimentally … time course data from two ecotypes of  Panicum hallii and multiple switchgrass ( Panicum virgatum ) experimental data. …
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JGI@25: Using Team Science to Build Communities Around Data
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … genomes that are both large and complex. The first publication of a genome generated by the OGG initiative — …
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Natural Prodcast Episode 4: Nancy Keller
… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Welcome back to Natural … Then you have to maybe improve some of your bioinformatic analysis. You don’t want to get clusters that are encoding …
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Bacteria and Fungi Divvy Up the Work in Forest Floor
… analyzing the enzymes present in the complex organic matrix of the forest floor, a team of researchers have found that there is a striking division … able to identify proteins, the team compiled DNA sequences (metagenomes) and messenger RNA sequences (transcriptomes) …
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Whole metagenome sequencing and 16S rRNA gene amplicon analyses reveal the complex microbiome responsible for the success of enhanced in-situ reductive dechlorination (ERD) of a tetrachloroethene-contaminated Superfund site
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JGI@25: Mapping Switchgrass Traits with Common Gardens
In honor of the JGI's 25th anniversary in 2022, we have revisited a … large polyploid genome, which means most genes are found as multiple copies across the chromosomes. In a follow-up study … (8X). They found that while the 8X variety was found in multiple states and environments, the 4X variety was more of …
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2024 Progress Report
… for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide … processed 13,700 metabolomics samples With our users, 247 publications were published   … Our primary objective is to … synthesis and other omics technologies with computational analysis and prediction. Together, and in an integrated …
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You Can Move, But You Can’t Hide
… to replicate themselves and spread from cell to cell. Two of the most common forms of MGEs are viruses and plasmids. They can be found in … currently has more than 700,000 plasmids from genomes, metagenomes and metatranscriptomes. To lower barriers to …
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Digging into Microbial Ecosystems Deep Underground
… “Microbes underpin so much of what we see on earth in terms of nutrient cycles and biogeochemical cycles…. Viruses play … Intent are due March 16, 2022 to freely access resources at multiple DOE user facilities through the FICUS research …
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Evolution of a Fungal Gene Expression Regulator
Describing the largest analysis to date of the modified DNA base 5mC variations in fungi. The … in fungi. A team of researchers reported on the largest analysis of 5mC distribution across the fungal tree of life …
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The Expanding Universe of Methane Metabolisms in Archaea
… gas 20 times more potent than carbon dioxide. Billions of years ago, methane-producing archaea likely played a key … from a variety of environments, as well as tools for analysis. “There is evidence that methanogenesis is one of … integrated high-throughput sequencing and computational analysis that enable systems-based scientific approaches to …
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