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Metabolism   Although there are still a large number of secondary metabolites yet to be discovered and their biosynthetic logics to be understood, accessing these untapped metabolic capabilities is often tedious and resource intensive. This is often due to, for example, tight regulation of biosynthetic gene clusters …

Thank you for joining us at the 2024 DOE Joint Genome Institute (JGI) Annual Genomics of Energy & Environment Meeting! The JGI convenes this …

… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory … regulation is critical to ensuring genes vital for growth and survival across various environments are … network in bacteria, enabling the discovery of regulatory cascades as well as crosstalk between sigma factors. While …

The latest edition of the JGI Progress Report highlights notable research and scientific collaborations in 2018. The cover is an image of Mono Lake, a saline soda lake east of California’s Yosemite National Park, taken by JGI’s own Jon …

Understanding the shared genetic toolkit of ancestral and present-day plants The Science In a recent  … thus allowing them to spread across most of the plant’s ecosystems. The Impact For decades, the liverwort  M. polymorpha has been used as a …

… event will bring together researchers across major ecosystems and disciplines who are developing and applying … studies.  This conference is inspired by the vision of standardized fabricated ecosystems (EcoFABs) designed for precise manipulation and reproducible experimentation of …

JGI is excited to announce the fifteen scientists selected for our 2024 Community Science Program Annual Call. “It’s exciting to see the diverse portfolio of successful CSP proposals this year,” noted Tanja Woyke, …

… a single protein. Recently reported in the Proceedings of the National Academy of Sciences , a team of researchers … research team included scientists at the University of California (UC), Berkeley, UCLA, UC Davis, Brookhaven National … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  …

Gilman, Louis Graf, Yuxi Guo, Shaomei He, Vayu Hill- Maini, Forrest Lefler, Pok Man (Bob) Leung and Huang Li; [middle] … You, Yong Zhang and Zhiping Zhong. (All images courtesy of the researchers) Each year, the JGI searches for novel … explore microbial and plant interactions across unique ecosystems, from alpine soils to tropical glaciers.  Proposals …

UC Merced students and their JGI mentors toasted to the end of a nine-week virtual internship. The celebration was … of this internship program, this was the largest turnout for the final presentations to date.  This summer internship … pandemic. As a result, mentors set up weekly, or in some cases daily, check-ins with their mentors to ensure projects …

This summer, the DOE JGI hosted 10 interns who came from a wide range of backgrounds. Many of them spent the summer crunching … analyses at their desks. As part of the DOE JGI’s efforts to promote diversity and inclusion in the sciences, …

A preview of how large-scale single cell genomics complements … approaches including amplicon and metagenomic sequencing. For example, they showed that the composition of the … a highly recombining microbial population. This work showcases the utility of single cell sequencing, as monitoring …