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JGI@25: From Life at the Extremes to Editing Genomes
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … led by Nikos Kyrpides , mining the Integrated Microbial Genomics & Microbiomes (IMG/M) system’s immense collection of … nature was using it to do something important.” Related Publications:  A scoutRNA Is Required for Some Type V …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… genome discoveries. Unlocking the intricate details of life’s genetic blueprint has long been a significant challenge in genomics. Enter GenomeOcean, a powerful generative model  now … ecological Harvard Forest project, large datasets from soil microbiome studies collected across various terrains, …
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Hiroshi Otani
… technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … BS, Engineering, Tokyo Institute of Technology Master's, Biotechnology, University of Tokyo PhD, Biotechnology, University of Tokyo … Udwary DW, Mouncey NJ. Comparative and pangenomic analysis of the genus Streptomyces. Sci Rep. 2022 Nov 7;12(1):18909. …
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SIPs with Standards
… SIP labwork and analysis can be very demanding.  The JGI offers SIP analysis to make these experiments accessible to … the goal is to generate SIP data that can be useful to multiple teams and analyses. This episode, Rex Malmstrom … more reusable, and more insightful, for the future of studying microbial communities.   …
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Introducing New Members of the JGI User Executive Committee
… JGI User Executive Committee (UEC) : Roland Hatzenpichler of Montana State University, Teresa Pawlowska of Cornell … review procedures and the organization of the JGI Annual Genomics of Energy & Meeting. Any investigator who has been an active user of the JGI at any time in the past two fiscal …
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iPHoP: A Matchmaker for Phages and their Hosts
… With metagenomic sequencing, researchers have found more of these viruses than ever before, in all kinds of … freely available online ). It combines and evaluates multiple predictions to reliably match viruses with their … microbiome data. In other environments, such as terrestrial soil, having additional isolates and metagenomic datasets …
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Products
… and pathway engineering Mass spectrometry based metabolomics Below is a table of standard product offerings, including a description of … at NCBI once the standard analysis is complete. Raw metabolomics data is submitted to the  MassIVE repository . Not all … DNA Synthesis Constructs <5kb in size Single gene or multiple small genes assembled to less than 5kb in length, …
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Defining the Sphagnum Core Microbiome across the North American Continent Reveals a Central Role for Diazotrophic Methanotrophs in the Nitrogen and Carbon Cycles of Boreal Peatland Ecosystems
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Better Genome Editing for Bioenergy
… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … level, how does  Y. lipolytica work? The project was a multi-institutional effort led by then-graduate student Cory … an initial screen using an unvetted library (with both active and inactive sgRNAs) appeared to be rife with false …
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JGI@25: Mapping Switchgrass Traits with Common Gardens
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … large polyploid genome, which means most genes are found as multiple copies across the chromosomes. In a follow-up study … and environments. The long-term investments in both the genomics and gardens are helping these shrubby grasses growing …
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Expanding Virophage Diversity
… in  Microbiome , researchers from the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office … datasets in JGI’s  Integrated Microbial Genomes & Microbiomes (IMG/M) data suite—which includes  IMG/VR (for … an early version of the paper at the 2018 Viral EcoGenomics & Applications (VEGA) Symposium. The work also used …
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JGI Announces FY26 Large Scale Portfolio for Our Community Science Program
… Hugh Cross; [Below] Zac Freedman, Martin Jonikas, Lotus Lofgren, Fumito Maruyama, Lauren Stadler, Tingting Xiang and … enzymes discovered in extreme environments to engineered microbiomes that accelerate biomass processing. This year’s … Microbiome Data Collaborative (NMDC) to produce open metagenomics data. Taking the JGI’s call for large-scale projects …
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