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Busting the Unbreakable Lignin
… of plant components   The Science There are three main ingredients to tackle when it comes to breaking down a … order to do so is a resource-intensive process. Now, a new study shows how anaerobic fungi — the kind living in the … wasn’t quite accurate, and maybe anaerobic fungi living in soils or the guts of livestock were more capable than …
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I-Min (Amy) Chen
Dr. I-Min A. Chen received her Ph.D. in Computer Science. Her … Palaniappan K, Ratner A, Chu K, Ritter SJ, Reddy TBK, Mukherjee S et al. IMG/VR v4: an expanded database of … I-MA et al. IMG/PR: a database of plasmids from genomes and metagenomes with rich annotations and metadata. Nucleic …
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Biotech Partners Summer Intern Co-Authors NAR Paper
Kaushal Sharma, one of five Antioch High School rising juniors who participated in internships at the DOE Joint Genome Institute this summer … his student’s contributions as reviewing close to 3,800 metagenomes to verify geographic locations and assign …
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Better Genome Editing for Bioenergy
… part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a … I will spend the first four sharpening the axe.” In this study,  published in  Metabolic Engineering , a team of … how to sharpen the CRISPR-Cas9 tool for a non-conventional eukaryotic host — an approach, the team says, that could be …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful … attempt to put them back into the original genomes. These metagenome-assembled genomes (MAGs) that came from shotgun … together, they found most bacterial genomes from water and soil communities were at least 80% complete when studied …
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
… gas, regulate Earth’s climate. Most methane is produced in environments without oxygen through a process called … confirmation bias, because it enables scientists to study how methanogenesis takes place in the context of the … They could just be switched off.” Yet, after extensive study, Hatzenpicher and his team were able to definitively …
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Gene Expression: From On-Off Switch to Dial
Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more … optimization. Summary Life is all about balance. This study,  recently published in the  Proceedings of the …
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New Research Finds Flagella in the Terrestrial Roots of Marine Bacteria
… s ditched their flagella and other traits when migrating back to the ocean. The Science Scientists have … unique array of chemicals not typically found in oceans or soils.  A recent study published in  The ISME Journal     focused on a class …
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Streamlining Regulon Identification in Bacteria
RIViT-seq technology could speed up associating transcription factors with their target genes. The … that control transcription. Summary Transcription in eukaryotes is handled by three distinct RNA polymerases; in … given sigma factor are inferred. Prior to this most recent study, only 12 sigma factors and 200 genes (or 209 sigma …
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JGI Earth Month: Wetlands Work in #TenHundredWords
Earth and DNA are close to our JGI hearts, we’re highlighting genomic science research that feels especially relevant to living on a changing planet. Mo Kaze is a University of … and metabolism, work on which she is expanding with her study of microbes in California’s manmade water transport …
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Boosting Small Molecule Production in Super “Soup”
Do metabolic pathways from engineered yeasts still work in cell-free environments? … of sustainable chemical products,” said Jewett, one of the study’s senior authors. “But this has been done most … graduate student Blake Rasor. He and Yi, one of the study co-authors, have maintained a regular shipment …
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JGI@25: Building a Better Bean
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements … to their economies. It also plays an important role in soil health through nitrogen-fixation and holds clues for …
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