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Uncovering secondary metabolite evolution and biosynthesis using gene cluster networks and genetic dereplication
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IMG-ABC: A Knowledge Base To Fuel Discovery of Biosynthetic Gene Clusters and Novel Secondary Metabolites
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Functional Genomics of Novel Secondary Metabolites from Diverse Cyanobacteria Using Untargeted Metabolomics
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Getting back to the grass roots: harnessing specialized metabolites for improved crop stress resilience
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Construction of Viable Soil Defined Media Using Quantitative Metabolomics Analysis of Soil Metabolites
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Root-associated bacterial communities and root metabolite composition are linked to nitrogen use efficiency in sorghum
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Waiting to Respire
… Genomes from uncultivated bacteria offers clues to ancestral bacteria’s energy sources. More … to gain and harness energy. As reported January 28, 2019 in Nature Communications , two research teams … Margulis). The information was then used to predict the metabolic strategies applied by a common ancestor to all …
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JGI Early Career Researchers Featured in mSystems Special Issue
… In a special issue of mSystems , out May 14, 2019, JGI researchers are among the authors who offer … compounds to link active microbes with specific metabolic processes. A third approach steps away from … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Pinning Down a Piece of Photosynthesis
… By studying the structure and function of a cyanobacterial protein, researchers have new insights … cycle carbon in changing conditions. The products of photosynthesis are easy to point out. Plants, algae and … and longtime JGI collaborator Sabeeha Merchant’s group. In 2011, they inventoried a swath of blueprints to find parts …
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Learning to Look
… “Where’s Waldo?” readers need to look for a number of distinguishing features. Several characters may be … glasses, or a cane, but only Waldo will have all of these features. As described July 22, 2019, in  Nature Microbiology , a team led by scientists … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Taking Stock of the Known and Unknown Microbial Space
… in sequencing technologies have led to an abundance of microbial genomes becoming available to the global research community.  Published January 17, 2025 in Science Advances , researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office …
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A Cost-Efficient Way to Convert Yeast into a Cell Factory for Hydroxyapatite
… hydroxyapatite, a high-value biomaterial with a wide range of industrial applications. The team was led by researchers at two U.S. Department of Energy national user facilities – the DOE Joint Genome … to make, and it could be sold in the United States for $50-200, generating a potential profit of $1.4 million …
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