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iPHoP: A Matchmaker for Phages and their Hosts
…   To understand virus-host dynamics, computation helps fill in what cultivation can’t. The Science At first, viruses are merely toolkits. To do anything, they must find a host, and not just any host will do. … microbiome data. In other environments, such as terrestrial soil, having additional isolates and metagenomic datasets …
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Viruses Reprogram Cells into Different Virocells
Microbial cells infected by viruses undergo metabolic reprogramming. The … The Ohio State University and the University of Michigan studying how virus infections cause significant metabolic … an experimental approach with a marine phage-host model to study virus-host-nutrient interactions. In  their study , …
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Help from Citrus’ Bitter, Hardier Cousin
… to disease-resistance that could prove fruitful for saving Citrus from greening disease. You’ve probably never … JGI collaborator, are senior authors of the  recent study published in  The Plant Journal.  this study included the discovery of candidate genes that confer …
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A Grass Model to Help Improve Giant Miscanthus
Miscanthus  sequence offers insights into benefits of polyploidy and perenniality. The … abilities to adapt to extreme environments such as poor soils and drought. The reference genome for M. sinensis, and … history and perennial lifecycle makes it important to study directly. The large and complex genome of M. sinensis …
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Engagement Webinar: Accessing NEON’s Environmental Sample Archives, Applying JGI & EMSL Omics Tools
… data to better understand how U.S. ecosystems are changing.  Through the  “Facilities Integrating Collaborations for User Science” (FICUS) call … Q:  Does NEON have or plan on collecting RNA samples from soil or surfaces for microbe-focused collections? A: Not at …
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Finding the Fermenters
Harnessing BER-funded data resources, researchers built an … an interactive browser that allows other researchers to study the genomes and predict the metabolic abilities of … also used the tool to predict possible functions from 733 metagenome-assembled rumen genomes. Finally, they used the …
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Extracting the Secrets of Secondary Metabolites
… for survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE … researchers with a powerful addition to their toolkit to study gene function. As a demonstration, the researchers …
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Busting the Unbreakable Lignin
… of plant components   The Science There are three main ingredients to tackle when it comes to breaking down a … order to do so is a resource-intensive process. Now, a new study shows how anaerobic fungi — the kind living in the … wasn’t quite accurate, and maybe anaerobic fungi living in soils or the guts of livestock were more capable than …
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I-Min (Amy) Chen
Dr. I-Min A. Chen received her Ph.D. in Computer Science. Her … I-MA et al. IMG/PR: a database of plasmids from genomes and metagenomes with rich annotations and metadata. Nucleic … Palaniappan K, and Chu K. Maintaining a Microbial Genome & Metagenome Data Analysis System in an Academic Setting, …
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Biotech Partners Summer Intern Co-Authors NAR Paper
Kaushal Sharma, one of five Antioch High School rising juniors who participated in internships at the DOE Joint Genome Institute this summer … his student’s contributions as reviewing close to 3,800 metagenomes to verify geographic locations and assign …
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Better Genome Editing for Bioenergy
… part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput gene-editing tool that can help scientists engineer organisms for … I will spend the first four sharpening the axe.” In this study,  published in  Metabolic Engineering , a team of …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful … attempt to put them back into the original genomes. These metagenome-assembled genomes (MAGs) that came from shotgun … together, they found most bacterial genomes from water and soil communities were at least 80% complete when studied …
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