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… for the global research community. The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) has released … jointgeno.me/2024StrategicPlan .) This plan aligns the DOE Office of Science user facility with broader national … solutions for bioproducts to support the bioeconomy. Functional diversity theme. Reading the genomes of …

… Understanding how a fundamental mechanism of evolution allows microbes to adapt to changing … cell’s membrane. Two decades ago, a team discovered a group of viruses that had in their genomes a surprising tool: a … that DGRs are not only widespread, but also surprisingly active. In viruses, DGRs appear to generate diversity …

… Mr. Everson rejoined the JGI in 2020  and leads all aspects of JGI Operations which include the Safety, Finance, Human … Joint Genome Institute after serving as the Chief Operating Officer of the DOE Joint Bioenergy Institute and the Operations … The Deputy of Operations provides oversight and leadership of JGI …

… Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical … an alternative format for chemical synthesis in the absence of cell growth by isolating the soluble components of lysed cells. By separating the production of enzymes (during growth) and the biochemical production …

… Dr. Blaby-Haas joined the JGI in 2022 as lead of the Biomolecular Materials Initiative, a partnership … at Berkeley Lab. She is spearheading the development of a joint user capability between the JGI and Molecular … Microbiology and Cell Science in 2011 from the University of Florida, working with Valérie de Crécy-Lagard on using …

… Joint Genome Institute and has focused on applying state-of-the-art molecular methods to address wide-ranging … Scientist at Lawrence Berkeley Laboratory, and Adjunct Professor at UC Berkeley. Dr. Pennacchio received his Ph.D in 1998 from the Department of Genetics at Stanford University where he uncovered the …

… genome discoveries. Unlocking the intricate details of life’s genetic blueprint has long been a significant … analyze but also create DNA sequences mimicking an array of microbial life. By leveraging massive user-generated … data. Trained on numerous versions of genes and enzymes, GenomeOcean can generate diverse types of enzyme …

… Interns contributed to a number of projects, from refining lab protocols at the bench to applying artificial intelligence to aspects of research questions Another intern summer has closed at … Bushnell Project:  Machine Learning Applications in Gene Annotation Masato Terasaki Mentor: Yumary Vasquez Project:  …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … of work; as sequencing technologies advanced, assembly and annotation of the genome sequence improved in parallel. The …

… survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … the researchers used CRAGE-CRISPR for discovering active secondary metabolites and helping them identify and … or activate certain genes and assess how these edits affect functionality.  CRAGE allows for the transplanting of these …

… Dr. Yasuo Yoshikuni has been head of the DNA Synthesis Science Program since 2015. The mission of this program is to harness the power of DNA synthesis, strain engineering, and biosystems design … at the JGI. Click to learn more about the program's areas of focus, major initiatives and more.  …

… get any sunlight, and yet they still support a unique array of microorganisms adapted to living in extreme conditions. … five oceanic regions. In doing so, they found a high degree of variability in the types of microorganisms that inhabit … in extreme environments. They also produce a range of novel enzymes and other biomolecules that could potentially be …