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Boosting Small Molecule Production in Super “Soup”
… Do metabolic pathways from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have both the … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s …
Learn more
Six join FICUS program in 2026
… The JGI is excited to welcome six to the Facilities Integrating Collaborations for User Facilities … (EMSL) and other national user facilities. Focus areas for these projects include biofuels, biomaterials and bioproducts; …
Learn more
JGI Early Career Researchers Featured in mSystems Special Issue
… In a special issue of mSystems , out May 14, 2019, JGI … before sequencing to recover rare microbes. The technique was applied to a recent Nature Communications paper, … in soil for the first time. A second approach known as DNA stable isotope probing (DNA SIP) relies on incubating …
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Neha Varghese
… Neha’s key role is to design, benchmark, and apply … community. She also provides support for user science and projects through implementation of advanced analysis pipelines and tools as well as development and implementation of microservices …
Learn more
Boosting Small Molecule Production in Super “Soup”
… Do metabolic pathways from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) Yeast strains engineered for the biochemical conversion of … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s …
Learn more
JGI announces 2024 New Investigator portfolio
… The JGI is eager to work and share our tools with a widening circle of … That’s why each year we look for novel research projects — aligned with DOE missions and from PIs who have … a range of projects spanning the resilience of desert grasslands to the metabolic savviness of microbial ecosystems …
Learn more
The fungus that made itself at home
… Retracing how the dry rot Serpula lacrymans adapted to a new … rot fungi reveals the genomic changes Serpula lacrymans has undergone in adapting to manmade environments. The Impact … brown rot Serpula lacrymans towards breaking down plant mass for conversion to sustainable, alternative biofuels and …
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A Mentor’s Perspective on Training the Next Generation
… Over the years, hundreds of interns have come to the JGI from all parts … the globe to gain lab experience and contribute to ongoing projects. In one way or another, they’ve all mentioned how invaluable their time at the JGI was and how great it was to have an experienced career …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… With a new methodology, scientists are now getting more complete … the microbiome of the earth, but most species do not grow easily in the lab. To access the genomes of uncultured  … cells and then amplifying their DNA for genome sequencing was no easy task. The traditional way of collecting them is …
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Mindfully Moving JGI
… JGI is in the process of shifting its operations from Walnut Creek to the heart of the Berkeley Lab … platforms were turned back on. A third sequencing platform was scheduled to resume production runs before the end of the … with annual one-day cleanups. During those days, they were asked to “KonMari” their spaces, a decluttering method …
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JGI@25: Expanding Metagenomics to Capture Viral Diversity
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and capabilities to enable great … soil, the sea and, of course, the cells of other organisms. As they infect microbes like bacteria, algae and protists, …
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JGI@25: Stories from Intern Alumni
… 2022 marks the JGI’s 25th anniversary . Over the next few months, … be revisiting a number of notable achievements that showcase our collaborations and capabilities to enable great … wet lab experiments, to computational modeling and virtual projects, hear intern alumni Candace Cole, Alessandro …
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