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… By characterizing the structure and function of a … sulfur from gaseous organic sulfur compounds in the atmosphere.  Beyond bacteria, this enzymatic machinery has … Program help advance DOE interests in the biotechnology innovation ecosystem. “At JGI, we’ve done the synthesis, …

… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary metabolites for multiple applications. Despite advances in sequencing technologies and computational … The U.S. Department of Energy Joint Genome Institute, a DOE Office of …

… The chromosome-scale genome sequence of trifoliate orange yields clues to … ways. It better tolerates cold, withstands pests, and, especially tantalizing, resists a disease ravaging citrus … analyzing the genome in order to find the genetic traits responsible for  P. trifoliata ’s hardiness, according to …

… Multi-species assays yield an unprecedented view of plant evolution and … akin to trying to chart every electrical connection in a sprawling metropolis — an overwhelming challenge due to … what a certain cell type looks like.” These recent innovations have propelled the creation of a vast resource: …

… For the Joint Genome Institute, the end of 2018 was marked by a celebration of contributing over one … of the Lab’s 200-acre campus—with the big move from leased space in Walnut Creek, Calif. scheduled to begin a month … Foundry, NERSC and ESnet, as well as externally to prospective partners to generate awareness of and clarity about …

… Trained on environmental data, a new JGI tool more accurately … meaning and relevance of new sequences. It can generate novel sequences based on the principles it learns from the … work with biotechnology companies including the bioeconomy space, trying to explore whether we can leverage this model …

… Fine-tuning metabolic gene expression helps identify variants in yeast … that were missed using traditional approaches. This novel form of intermediate expression, when used in addition … on these sugars. To demonstrate the versatility of this novel technique, Alper and his team also applied this method …

… Mini-Metagenomics Approach Helps Identify Novel Archaeal Methane … report the discovery of a novel archaeum from a hot spring that has the genetic machinery to perform … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility located at Lawrence …

… A collaborative team led by Geoffrey Schiebinger at the … a foundation for still larger efforts in diverse plant species beyond models,” he said. Cole annotated cell types … for this purpose is “particularly applicable for non-model species for which fewer ‘marker’ genes are known that are …

… New Graduate Internship Program Builds Bridges Between DOE JGI, UC … with research interests in computational biology, I was especially intrigued by this program, as it will foster … take place on the UC Merced campus in late October or early November, at which time they will receive certificates. With …

… Chloroplast mimic a platform to capture and utilize carbon in a … Photosynthesis harnesses carbon captured from the atmosphere in a process that generates energy. The MPI team … library remains a foundational asset that allows them to innovate by screening for well-performing CO2-fixing enzymes …

… A “bait and hook” single-cell genomic approach to … community from geothermal hot springs, they uncovered a novel cellulose-degrading bacterium typically found in low … The work conducted by the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility, is supported under …