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Gut Fungi: Unexpected Source of Novel Chemicals
Swift — verified that the fungi expressed biosynthetic gene clusters, which are “building blocks” of natural … products. The team then confirmed that these expressed genes translated into expected proteins. That work was done … fungal natural products, O’Malley and her team plan to use genetic tools to boost production and isolate the compounds. …
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Igor Grigoriev
Russia PhD in Molecular Biology, Research Institute for Genetics and Selection of Industrial Organisms, Moscow, … atlas of mushroom development reveals conserved genes behind complex multicellularity in fungi. Proc Natl … … Fungal & Algal Science Program … Education … Selected Publications … Awards and Service …
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Evolutionary instability of CUG-Leu in the genetic code of budding yeasts
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Yasuo Yoshikuni
University of Washington … Shen et al., Mitochondrial ATP generation is more proteome efficient than glycolysis., … characterization of a soil viral auxiliary metabolic gene product - a functional chitosanase., Nature … … DNA Synthesis Science Program … Education … Selected Publications … Awards and Honors …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… contains about 6% of the human genome . They discovered genes linked to conditions such as cardiovascular disease, … about 2% of the human genome. They were interested in genes involved in repair of DNA damage, and those associated … with the HudsonAlpha Institute for Biotechnology. Publications Grimwood, J., Gordon, L., Olsen, A. et al. The …
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Learning to Look
As their small genomes can be easily manipulated through genetic engineering, inoviruses are used for several … “What we’re really doing is looking for a particular gene found in all inoviruses, and then checking the surrounding genes,” he said. “If these genes are similar in size and …
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Forming Scientific Connections and Building Community
… here.” Mentor: Lorenzo Aureli Project: “ Exploring the epigenetic basis of pathogenicity in bacteria” Erika Maquiling … Mentor: Zhong Wang Project: “ Improving biosynthetic gene cluster annotation by leveraging a large genomic model … a multiplex genomic integration system for the selection of genes essential for specialized carbon utilization ” Jesica …
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You Can Move, But You Can’t Hide
… develop a tool to quickly and accurately identify mobile genetic elements like plasmids and viruses. The Science Mobile genetic elements (MGEs) are genetic entities that seek to replicate themselves and …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
Then, using metagenomes and metatranscriptomes generated by the U.S. Department of Energy (DOE) Joint … genomes, they found a huge variety of CRISPR-Cas systems. Generally, prokaryotes use CRISPR-Cas systems to recognize … systems, the CRISPR-Cas9 system, is a powerful tool in gene editing, but many other systems exist. Investigating …
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Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens
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A chromosome-scale genome assembly and dense genetic map for Xenopus tropicalis
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The future of legume genetic data resources: Challenges, opportunities, and priorities
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